Biocatalysis has an enormous impact on chemical synthesis. The waves in which
biocatalysis has developed, and in doing so changed our perception of what organic …

The role and power of biocatalysis in sustainable chemistry has been continuously brought
forward step by step to its present outstanding position. The problem‐solving capabilities of …

The ever increasing industrial production of commodity and specialty chemicals inexorably
depletes the finite primary fossil resources available on Earth. The forecast of population …

Enzymes are outstanding (bio) catalysts, not solely on account of their ability to increase
reaction rates by up to several orders of magnitude but also for the high degree of substrate …

Amide bonds occur in over half of target compounds in medicinal chemistry patents, making
amide bond formation the most commonly performed reaction in the pharmaceutical …

In this Perspective we show how an expansion of the scope and impact of biocatalysis in
industrial organic synthesis is enabled by streamlining the underpinning biocatalyst and …

Enzymatic immobilization has been at the forefront of applied biocatalysis as it enables
convenient isolation and reuse of the catalyst if the target reaction is conducted in batch, and …

Highlights•Enzyme immobilization is a key enabling technology for flow
biocatalysis.•Materials and immobilization protocols need to be adapted for continuous …

Highlights•Process intensification through upstream and downstream processing is an
important tool to increase the overall productivity of continuous biocatalysis.•Immobilization …

Biocatalysts represent an efficient, highly selective and greener alternative to metal catalysts
in both industry and academia. In the last two decades, the interest in biocatalytic …