The Rab family of small GTPases regulates intracellular membrane trafficking by
orchestrating the biogenesis, transport, tethering, and fusion of membrane‐bound …

The eukaryotic endomembrane system consists of multiple interconnected organelles. Rab
GTPases are organelle-specific markers that give identity to these membranes by recruiting …

Eukaryotic cells maintain a highly organized endolysosomal system. This system regulates
the protein and lipid content of the plasma membrane, it participates in the intracellular …

In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …

In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …

Several of the most important discoveries in the field of membrane traffic have come from
studies of Rab GTPases by Marino Zerial and Peter Novick and their colleagues. Zerial was …

Exosomes are extracellular vesicles released upon fusion of multivesicular bodies (MVBs)
with the cellular plasma membrane. They originate as intraluminal vesicles (ILVs) during the …

Platelet granules are unique among secretory vesicles in both their content and their life
cycle. Platelets contain three major granule types—dense granules, α-granules, and …

Lysosome‐related organelles (LROs) comprise a diverse group of cell type‐specific,
membrane‐bound subcellular organelles that derive at least in part from the endolysosomal …

Protein and lipid transport along the endolysosomal system of eukaryotic cells depends on
multiple fusion and fission events. Over the past few years, the molecular constituents of …