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Nanocatalyzed synthetic approach for quinazoline and quinazolinone derivatives: A review (2015–present)
Quinazolines and their derivative are among the most significant heterocyclic compounds
due to their several chemical reactivities and vital range of biological activity. Although a …
due to their several chemical reactivities and vital range of biological activity. Although a …
Efficient synthesis and molecular docking analysis of quinazoline and azole hybrid derivatives as promising agents for anti-cancer and anti-tuberculosis activities
Molecular docking is a computational method based on bioinformatics that simulates the
interaction dynamics of molecules such as ligands and receptors, predicting their binding …
interaction dynamics of molecules such as ligands and receptors, predicting their binding …
Visible light-mediated synthesis of quinazolinones from benzyl bromides and 2-aminobenzamides without using any photocatalyst or additive
S Huang, L **, Y Liu, G Yang, A Wang, Z Le… - Organic & …, 2024 - pubs.rsc.org
This paper reports a novel method for the visible-light-mediated synthesis of quinazolinones
from the reaction of benzyl bromides with 2-aminobenzamides. The reaction proceeded …
from the reaction of benzyl bromides with 2-aminobenzamides. The reaction proceeded …
Synthesis, biological evaluation, and computational studies of some novel quinazoline derivatives as anticancer agents
A series of quinazolinone derivatives (7a–7h) were synthesized as antiproliferative agents.
All compounds, were synthesized through three steps method and structurally evaluated by …
All compounds, were synthesized through three steps method and structurally evaluated by …
NNO pincer ligand-supported palladium (II) complexes: direct synthesis of quinazolines via acceptorless double dehydrogenative coupling of alcohols
A sustainable approach for the synthesis of substituted quinazolines by sequential
acceptorless dehydrogenative coupling of 2-aminobenzyl alcohol with alcohols using new …
acceptorless dehydrogenative coupling of 2-aminobenzyl alcohol with alcohols using new …
An updated overview on the synthesis and anticancer evaluation of quinazoline derivatives
J Kaur, S Kaur, A Anand, N Islam, S Singh… - …, 2023 - Wiley Online Library
Cancer, a leading global cause of death, necessitates the exploration of safer and more
effective anticancer drugs due to the adverse side effects associated with current cytotoxic …
effective anticancer drugs due to the adverse side effects associated with current cytotoxic …
Design, synthesis, in-silico studies and apoptotic activity of novel amide enriched 2-(1H)-quinazolinone derivatives
Cancer is a broad classification of diseases that can affect any organ or body tissue due to
aberrant cellular proliferation for unknown reasons. Many present chemotherapeutic drugs …
aberrant cellular proliferation for unknown reasons. Many present chemotherapeutic drugs …
Design and synthesis of quinazolinone-triazole hybrids as potent anti-tubercular agents
A straightforward and convenient methodology has been developed for the reaction of 2-
aminobenzamide and carbonyls affording 2, 3-dihydroquinazolin-4 (1 H)-ones using …
aminobenzamide and carbonyls affording 2, 3-dihydroquinazolin-4 (1 H)-ones using …
Biology of quinoline and quinazoline alkaloids
XF Shang, SL Morris-Natschke, YQ Liu, XH Li… - The Alkaloids: Chemistry …, 2022 - Elsevier
Quinoline and quinazoline alkaloids, two important classes of N-based heterocyclic
compounds, have attracted scientific and popular interest worldwide since the 19th century …
compounds, have attracted scientific and popular interest worldwide since the 19th century …
Advances in the application of 1, 2, 4-triazole-containing hybrids as anti-tuberculosis agents
Y Cao, H Lu - Future Medicinal Chemistry, 2021 - Taylor & Francis
Tuberculosis is a deadly communicable disease caused by the bacillus Mycobacterium
tuberculosis (MTB), and pulmonary tuberculosis accounts for over 80% of the total cases …
tuberculosis (MTB), and pulmonary tuberculosis accounts for over 80% of the total cases …