Objectives This study sought to estimate and compare the aggregate treatment benefit of
pharmacological therapy for heart failure (HF) with reduced ejection fraction. Background …

The first edition of the clinical practice guidelines for liver cirrhosis was published in 2010,
and the second edition was published in 2015 by the Japanese Society of Gastroenterology …

Importance Current rehabilitation guidelines for patients with post–COVID-19 condition
(PCC) are primarily based on expert opinions and observational data, and there is an urgent …

Multimorbidity (two or more coexisting conditions in an individual) is a growing global
challenge with substantial effects on individuals, carers and society. Multimorbidity occurs a …

Objective To provide guidance to rheumatology providers on the use of coronavirus disease
2019 (COVID‐19) vaccines for patients with rheumatic and musculoskeletal diseases …

Background High-flow nasal cannula (HFNC) has become a frequently used noninvasive
form of respiratory support in acute settings; however, evidence supporting its use has only …

Data continue to accumulate indicating that many systematic reviews are methodologically
flawed, biased, redundant, or uninformative. Some improvements have occurred in recent …

Background Emerging fungal pathogens pose important threats to global public health. The
World Health Organization has responded to the rising threat of traditionally neglected …

The number of deaths from colorectal cancer in Japan continues to increase. Colorectal
cancer deaths exceeded 50,000 in 2016. In the 2019 edition, revision of all aspects of …

Objective We conducted a systematic review and meta-analysis to clarify the effects of
different exercise modes (resistance training [RT], whole body vibration training [WBVT], and …