[HTML][HTML] α-Synuclein misfolding and Parkinson's disease
Substantial evidence links α-synuclein, a small highly conserved presynaptic protein with
unknown function, to both familial and sporadic Parkinson's disease (PD). α-Synuclein has …
unknown function, to both familial and sporadic Parkinson's disease (PD). α-Synuclein has …
Copper, zinc and iron in neurodegenerative diseases (Alzheimer's, Parkinson's and prion diseases)
The basic role of metal ions including copper, zinc and iron in neurological pathologies is
generally accepted. The relationship between the development of disease and particular …
generally accepted. The relationship between the development of disease and particular …
A pesticide and iPSC dopaminergic neuron screen identifies and classifies Parkinson-relevant pesticides
Parkinson's disease (PD) is a complex neurodegenerative disease with etiology rooted in
genetic vulnerability and environmental factors. Here we combine quantitative …
genetic vulnerability and environmental factors. Here we combine quantitative …
Recent advances (2017–20) in the detection of copper ion by using fluorescence sensors working through transfer of photo-induced electron (PET), excited-state …
An essential trace element copper plays several physiological roles in living systems. But at
excess concentration, it exerts toxicity and becomes associated with numerous disorders. In …
excess concentration, it exerts toxicity and becomes associated with numerous disorders. In …
A chemical probe capable for fluorescent and colorimetric detection to Cu2+ and CN− based on coordination and nucleophilic addition mechanism
L Wang, ZL Wei, ZZ Chen, C Liu, WK Dong… - Microchemical Journal, 2020 - Elsevier
A salamo-like chemical probe HL with novel structure for continuous recognition of Cu 2+
and CN− was synthesized by Schiff base reaction. Some meticulous researches on the …
and CN− was synthesized by Schiff base reaction. Some meticulous researches on the …
A novel “on-off-on” halogen-substituted bis (salamo)-like fluorogenic chemosensor for sequentially identifying Cu2+ ions and cysteine
ZF Hu, L Dou, J Zhang, Y Zhang, YX Sun… - Inorganica Chimica …, 2022 - Elsevier
A novel bis (salamo)-like fluorogenic chemosensor (BDS) was designed for recognition Cu
2+ ions through fluorescence “off” in DMSO/H 2 O (v/v= 9: 1) Tris-HCl (pH= 7.26) buffer …
2+ ions through fluorescence “off” in DMSO/H 2 O (v/v= 9: 1) Tris-HCl (pH= 7.26) buffer …
A new multifunctional rhodamine-derived probe for colorimetric sensing of Cu (II) and Al (III) and fluorometric sensing of Fe (III) in aqueous media
A new rhodamine-derived Schiff base RH was synthesized and its sensing behavior toward
various metal ions was investigated by UV–vis and fluorescence spectroscopic techniques …
various metal ions was investigated by UV–vis and fluorescence spectroscopic techniques …
[HTML][HTML] DNA tetrahedral nanostructures for the biomedical application and spatial orientation of biomolecules
W Wang, M Lin, W Wang, Z Shen, ZS Wu - Bioactive Materials, 2024 - Elsevier
DNA not only plays a vital role in nature as fundamental hereditary material for storing
genetic material, but also serves as well-defined functional material, for example, building …
genetic material, but also serves as well-defined functional material, for example, building …
Alpha-synuclein is a cellular ferrireductase
α-synuclein (αS) is a cellular protein mostly known for the association of its aggregated
forms with a variety of diseases that include Parkinson's disease and Dementia with Lewy …
forms with a variety of diseases that include Parkinson's disease and Dementia with Lewy …
A highly selective thiosemicarbazone based Schiff base chemosensor for colorimetric detection of Cu2+ and Ag+ ions and turn-on fluorometric detection of Ag+ ions
A colorimetric and fluorometric turn-on probe L,(E)-1-((pyridin-4-yl) methylene)
thiosemicarbazide has been synthesized and characterized by X-ray single crystal analysis …
thiosemicarbazide has been synthesized and characterized by X-ray single crystal analysis …