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Brain circuit dysfunction in post-traumatic stress disorder: from mouse to man
Post-traumatic stress disorder (PTSD) is a prevalent, debilitating and sometimes deadly
consequence of exposure to severe psychological trauma. Although effective treatments …
consequence of exposure to severe psychological trauma. Although effective treatments …
Post-traumatic stress disorder
Post-traumatic stress disorder (PTSD) occurs in 5–10% of the population and is twice as
common in women as in men. Although trauma exposure is the precipitating event for PTSD …
common in women as in men. Although trauma exposure is the precipitating event for PTSD …
Fear and the defense cascade: clinical implications and management
K Kozlowska, P Walker, L McLean… - Harvard review of …, 2015 - journals.lww.com
Evolution has endowed all humans with a continuum of innate, hard-wired, automatically
activated defense behaviors, termed the defense cascade. Arousal is the first step in …
activated defense behaviors, termed the defense cascade. Arousal is the first step in …
How does eye movement desensitization and reprocessing therapy work? A systematic review on suggested mechanisms of action
Background: Eye movement desensitization and reprocessing [EMDR] is an innovative,
evidence-based and effective psychotherapy for post-traumatic stress disorder [PTSD]. As …
evidence-based and effective psychotherapy for post-traumatic stress disorder [PTSD]. As …
Post-traumatic stress disorder: the neurobiological impact of psychological trauma
JE Sherin, CB Nemeroff - Dialogues in clinical neuroscience, 2011 - Taylor & Francis
The classic fight-or-flight response to perceived threat is a reflexive nervous phenomenon
thai has obvious survival advantages in evolutionary terms. However, the systems that …
thai has obvious survival advantages in evolutionary terms. However, the systems that …
Emotion regulation: quantitative meta-analysis of functional activation and deactivation
Emotion regulation is hypothesized to be a multifaceted process by which individuals
willfully modulate the intensity and direction of emotional response via prefrontally mediated …
willfully modulate the intensity and direction of emotional response via prefrontally mediated …
Neuroimaging of child abuse: a critical review
H Hart, K Rubia - Frontiers in human neuroscience, 2012 - frontiersin.org
Childhood maltreatment is a stressor that can lead to the development of behavior problems
and affect brain structure and function. This review summarizes the current evidence for the …
and affect brain structure and function. This review summarizes the current evidence for the …
The neurocircuitry of fear, stress, and anxiety disorders
Anxiety disorders are a significant problem in the community, and recent neuroimaging
research has focused on determining the brain circuits that underlie them. Research on the …
research has focused on determining the brain circuits that underlie them. Research on the …
Functional neuroimaging of anxiety: a meta-analysis of emotional processing in PTSD, social anxiety disorder, and specific phobia
Objective: The study of human anxiety disorders has benefited greatly from functional
neuroimaging approaches. Individual studies, however, vary greatly in their findings. The …
neuroimaging approaches. Individual studies, however, vary greatly in their findings. The …
Neurobiological basis of failure to recall extinction memory in posttraumatic stress disorder
BACKGROUND: A clinical characteristic of posttraumatic stress disorder (PTSD) is
persistently elevated fear responses to stimuli associated with the traumatic event. The …
persistently elevated fear responses to stimuli associated with the traumatic event. The …