Currently, gliomas are diagnosed by neuroimaging, and refined diagnosis requires
resection or biopsy to obtain tumour tissue for histopathological classification and grading …

Liquid biopsy represents a minimally invasive procedure that can provide similar information
from body fluids to what is usually obtained from a tissue biopsy sample. Its implementation …

Purpose: Glioblastoma (GBM) is the most common primary brain tumor. The identification of
blood biomarkers reflecting the tumor status represents a major unmet need for optimal …

Bayesian networks are a type of probabilistic graphical models lie at the intersection
between statistics and machine learning. They have been shown to be powerful tools to …

Accurate circulating biomarkers have potential clinical applications in population screening,
tumor subclassification, monitoring tumor status, and the delivery of individualized …

Molecular biomarkers in blood are needed to aid the early diagnosis and clinical
assessment of glioblastoma (GBM). Here, in order to identify biomarker candidates in …

Haptoglobin (Hp) is a glycoprotein that binds free hemoglobin (Hb) in plasma and plays a
critical role in tissue protection and prevention of oxidative damage. Besides, it has some …

Background Gliomas are the most common and aggressive tumors of the central nervous
system. A robust and widely used blood-based biomarker for glioma has not yet been …

Analysis of the cerebrospinal fluid (CSF) proteome has proven valuable to the study of
neurodegenerative disorders. To identify new protein/pathway alterations and candidate …

Glioblastoma multiforme (GBM) is a primary type of lethal brain tumor. Over the last two
decades, temozolomide (TMZ) has remained the primary chemotherapy for GBM. However …