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Glioblastoma therapy: Past, present and future
E Obrador, P Moreno-Murciano… - International journal of …, 2024 - mdpi.com
Glioblastoma (GB) stands out as the most prevalent and lethal form of brain cancer.
Although great efforts have been made by clinicians and researchers, no significant …
Although great efforts have been made by clinicians and researchers, no significant …
[HTML][HTML] Advancements in glioma care: Focus on emerging neurosurgical techniques
Background: Despite significant advances in understanding the molecular pathways of
glioma, translating this knowledge into effective long-term solutions remains a challenge …
glioma, translating this knowledge into effective long-term solutions remains a challenge …
Nanoparticle-based combinational strategies for overcoming the blood-brain barrier and blood-tumor barrier
SH Lim, GT Yee, D Khang - International Journal of Nanomedicine, 2024 - Taylor & Francis
The blood-brain barrier (BBB) and blood-tumor barrier (BTB) pose substantial challenges to
efficacious drug delivery for glioblastoma multiforme (GBM), a primary brain tumor with poor …
efficacious drug delivery for glioblastoma multiforme (GBM), a primary brain tumor with poor …
[HTML][HTML] Preclinical models and technologies in Glioblastoma Research: evolution, current state, and future avenues
Glioblastoma is the most common malignant primary central nervous system tumor and one
of the most debilitating cancers. The prognosis of patients with glioblastoma remains poor …
of the most debilitating cancers. The prognosis of patients with glioblastoma remains poor …
Peritumoral brain zone in glioblastoma: Biological, clinical and mechanical features
Glioblastoma is a highly aggressive and invasive tumor that affects the central nervous
system (CNS). With a five-year survival rate of only 6.9% and a median survival time of eight …
system (CNS). With a five-year survival rate of only 6.9% and a median survival time of eight …
Sonodynamic therapy and magnetic resonance-guided focused ultrasound: New therapeutic strategy in glioblastoma
L Bonosi, S Marino, UE Benigno, S Musso… - Journal of neuro …, 2023 - Springer
Glioblastoma (GB) is one of the most aggressive and difficult-to-treat brain tumors, with a
poor prognosis and limited treatment options. In recent years, sonodynamic therapy (SDT) …
poor prognosis and limited treatment options. In recent years, sonodynamic therapy (SDT) …
A Roadmap of CAR-T-cell therapy in glioblastoma: Challenges and future perspectives
Glioblastoma (GBM) is the most common primary malignant brain tumor, with a median
overall survival of less than 2 years and a nearly 100% mortality rate under standard therapy …
overall survival of less than 2 years and a nearly 100% mortality rate under standard therapy …
A phase I clinical trial of sonodynamic therapy combined with temozolomide in the treatment of recurrent glioblastoma
B Zha, J Yang, Q Dang, P Li, S Shi, J Wu, H Cui… - Journal of neuro …, 2023 - Springer
Purpose The prognosis of recurrent glioblastoma (rGBM) is poor, and there is currently no
effective treatment strategy. Sonodynamic therapy (SDT) is a new method for cancer …
effective treatment strategy. Sonodynamic therapy (SDT) is a new method for cancer …
Long-acting therapeutic delivery systems for the treatment of gliomas
Despite the emergence of cutting-edge therapeutic strategies and tremendous progress in
research, a complete cure of glioma remains elusive. The heterogenous nature of tumor …
research, a complete cure of glioma remains elusive. The heterogenous nature of tumor …
[HTML][HTML] Current clinical investigations of focused ultrasound blood-brain barrier disruption: a review
The blood-brain barrier (BBB) presents a formidable challenge in delivering therapeutic
agents to the central nervous system. Ultrasound-mediated BBB disruption has emerged as …
agents to the central nervous system. Ultrasound-mediated BBB disruption has emerged as …