Regulation of mitochondrial physiology requires an efficient exchange of molecules
between mitochondria and the cytoplasm via the outer mitochondrial membrane (OMM). The …

Here, we review current evidence pointing to the function of VDAC1 in cell life and death,
and highlight these functions in relation to cancer. Found at the outer mitochondrial …

Several types of channels play a role in the maintenance of ion homeostasis in subcellular
organelles including endoplasmatic reticulum, nucleus, lysosome, endosome, and …

Increasing evidences suggest that mitochondrial dysfunction plays an important role in the
pathogenesis of neurodegenerative diseases including Alzheimer's disease (AD) …

Among the permeability pathways in the mitochondrial outer membrane (MOM), whose
elucidation was pioneered by Kathleen Kinnally, there is one formed by the lipid, ceramide …

An increased flux of potassium ions into the mitochondrial matrix through the ATP-sensitive
potassium channel (mitoKATP) has been shown to provide protection against ischemia …

Abstract Ischemia/reperfusion (I/R) is a well‐known injury to the myocardium, but the
mechanism involved remains elusive. In addition to the well‐accepted apoptosis theory …

Mitochondria are essential intracellular organelles that regulate energy metabolism, cell
death, and signaling pathways that are important for cell proliferation and differentiation …

Lung cancer is one of the leading causes of cancer-related deaths worldwide. The Ca2+-
activated K+ channel KCa3. 1 contributes to the progression of non-small cell lung cancer …

Highlights•Scutellaria pinnatifida A. Ham.(Lamiaceae) is a herb that is used in traditional
medicine of eastern countries.•Wogonin and neobicalein are flavonoids that are isolated …