Psychosis in Alzheimer disease—mechanisms, genetics and therapeutic opportunities

Z Ismail, B Creese, D Aarsland, HC Kales… - Nature Reviews …, 2022 - nature.com
Psychosis is a common and distressing symptom in people with Alzheimer disease, and few
safe and effective treatments are available. However, new approaches to symptom …

Brain mechanisms underlying neuropsychiatric symptoms in Alzheimer's disease: a systematic review of symptom-general and–specific lesion patterns

Y Chen, M Dang, Z Zhang - Molecular Neurodegeneration, 2021 - Springer
Neuropsychiatric symptoms (NPSs) are common in patients with Alzheimer's disease (AD)
and are associated with accelerated cognitive impairment and earlier deaths. This review …

[BUCH][B] Social isolation and loneliness in older adults: Opportunities for the health care system

National Academies of Sciences… - 2020 - books.google.com
Social isolation and loneliness are serious yet underappreciated public health risks that
affect a significant portion of the older adult population. Approximately one-quarter of …

Defeating Alzheimer's disease and other dementias: a priority for European science and society

B Winblad, P Amouyel, S Andrieu, C Ballard… - The Lancet …, 2016 - thelancet.com
Executive summary Alzheimer's disease (AD) is the leading cause of dementia, and
because the primary risk factor for AD is old age, the prevalence of the disease is increasing …

The effect of music therapy on cognitive functions in patients with Alzheimer's disease: a systematic review of randomized controlled trials

M Bleibel, A El Cheikh, NS Sadier… - Alzheimer's Research & …, 2023 - Springer
Background The use of music interventions as a non-pharmacological therapy to improve
cognitive and behavioral symptoms in Alzheimer's disease (AD) patients has gained …

Assessment and management of behavioral and psychological symptoms of dementia

HC Kales, LN Gitlin, CG Lyketsos - Bmj, 2015 - bmj.com
Behavioral and psychological symptoms of dementia include agitation, depression, apathy,
repetitive questioning, psychosis, aggression, sleep problems, wandering, and a variety of …

[HTML][HTML] Systematic review of systematic reviews of non-pharmacological interventions to treat behavioural disturbances in older patients with dementia. The …

I Abraha, JM Rimland, FM Trotta, G Dell'Aquila… - BMJ open, 2017 - bmjopen.bmj.com
Objective To provide an overview of non-pharmacological interventions for behavioural and
psychological symptoms in dementia (BPSD). Design Systematic overview of reviews. Data …

The Mild Behavioral Impairment Checklist (MBI-C): a rating scale for neuropsychiatric symptoms in pre-dementia populations

Z Ismail, L Agüera-Ortiz, H Brodaty… - Journal of …, 2017 - journals.sagepub.com
Background: Mild behavioral impairment (MBI) is a construct that describes the emergence
at≥ 50 years of age of sustained and impactful neuropsychiatric symptoms (NPS), as a …

[HTML][HTML] Neuropsychiatric signs and symptoms of Alzheimer's disease: New treatment paradigms

KL Lanctôt, J Amatniek, S Ancoli-Israel… - Alzheimer's & Dementia …, 2017 - Elsevier
Neuropsychiatric symptoms (NPSs) are hallmarks of Alzheimer's disease (AD), causing
substantial distress for both people with dementia and their caregivers, and contributing to …

Neuropsychiatric symptoms in elderly with dementia during COVID-19 pandemic: definition, treatment, and future directions

A Simonetti, C Pais, M Jones, MC Cipriani… - Frontiers in …, 2020 - frontiersin.org
Background Neuropsychiatric symptoms (NPS) of dementia, such as anxiety, depression,
agitation, and apathy, are complex, stressful, and costly aspects of care, and are associated …