Brain function critically depends on a close matching between metabolic demands,
appropriate delivery of oxygen and nutrients, and removal of cellular waste. This matching …

Neuroticism is one of the most robust higher-order personality traits associated with negative
emotionality and risk of mental disorders. Many studies have investigated relationships …

X-ray-computed tomography (CT) is a well-established tissueimaging technique employed
in a variety of research and clinical settings. 1 Specifically, CT is a noninvasive clinical …

Diffuse correlation spectroscopy (DCS) uses the temporal fluctuations of near-infrared (NIR)
light to measure cerebral blood flow (CBF) non-invasively. Here, we provide a brief history of …

Arterial spin labeling (ASL) is a non-invasive MRI technique to measure cerebral blood flow
(CBF). This review provides a practical guide and overview of the clinical applications of …

This review describes the diffusion model for light transport in tissues and the medical
applications of diffuse light. Diffuse optics is particularly useful for measurement of tissue …

Magnetic particle imaging is an emerging tomographic technique with the potential for
simultaneous high-resolution, high-sensitivity, and real-time imaging. Magnetic particle …

There is considerable utility in the use of transcranial Doppler ultrasound (TCD) to assess
cerebrovascular function. The brain is unique in its high energy and oxygen demand but …

Cerebrovascular reactivity is the change in cerebral blood flow in response to a vasodilatory
or vasoconstrictive stimulus. Measuring variations of cerebrovascular reactivity between …

The response of cerebral vasculature to exercise is different from other peripheral
vasculature; it has a small vascular bed and is strongly regulated by cerebral autoregulation …