MicroRNAs as regulatory elements in immune system logic
A Mehta, D Baltimore - Nature Reviews Immunology, 2016 - nature.com
MicroRNAs (miRNAs) are crucial post-transcriptional regulators of haematopoietic cell fate
decisions. They act by negatively regulating the expression of key immune development …
decisions. They act by negatively regulating the expression of key immune development …
MicroRNA regulation of atherosclerosis
MW Feinberg, KJ Moore - Circulation research, 2016 - Am Heart Assoc
Atherosclerosis and its attendant clinical complications, such as myocardial infarction,
stroke, and peripheral artery disease, are the leading cause of morbidity and mortality in …
stroke, and peripheral artery disease, are the leading cause of morbidity and mortality in …
The IL-23–IL-17 immune axis: from mechanisms to therapeutic testing
Following the discovery of T helper 17 (TH17) cells, the past decade has witnessed a major
revision of the TH subset paradigm and substantial progress has been made in deciphering …
revision of the TH subset paradigm and substantial progress has been made in deciphering …
Exosome-derived microRNAs of human milk and their effects on infant health and development
BC Melnik, W Stremmel, R Weiskirchen, SM John… - Biomolecules, 2021 - mdpi.com
Multiple biologically active components of human milk support infant growth, health and
development. Milk provides a wide spectrum of mammary epithelial cell-derived …
development. Milk provides a wide spectrum of mammary epithelial cell-derived …
miR-146 and miR-155: two key modulators of immune response and tumor development
U Testa, E Pelosi, G Castelli, C Labbaye - Non-coding RNA, 2017 - mdpi.com
MicroRNAs (miRNAs or miRs) are a class of evolutionarily-conserved small, regulatory non-
coding RNAs, 19–3 nucleotides in length, that negatively regulate protein coding gene …
coding RNAs, 19–3 nucleotides in length, that negatively regulate protein coding gene …
New concepts in cancer biomarkers: circulating miRNAs in liquid biopsies
The effective and efficient management of cancer patients relies upon early diagnosis and/or
the monitoring of treatment, something that is often difficult to achieve using standard tissue …
the monitoring of treatment, something that is often difficult to achieve using standard tissue …
MicroRNA-155—at the critical interface of innate and adaptive immunity in arthritis
MicroRNAs (miRNAs) are small non-coding RNAs that fine-tune the cell response to a
changing environment by modulating the cell transcriptome. miR-155 is a multifunctional …
changing environment by modulating the cell transcriptome. miR-155 is a multifunctional …
MicroRNA involvement in signaling pathways during viral infection
MG Barbu, CE Condrat, DC Thompson… - Frontiers in cell and …, 2020 - frontiersin.org
The study of miRNAs started in 1993, when Lee et al. observed their involvement in the
downregulation of a crucial protein known as LIN-14 in the nematode Caenorhabditis …
downregulation of a crucial protein known as LIN-14 in the nematode Caenorhabditis …
MicroRNA-155 negatively affects blood-brain barrier function during neuroinflammation.
MA Lopez-Ramirez, D Wu, G Pryce, JE Simpson… - FASEB journal, 2014 - oro.open.ac.uk
Blood-brain barrier (BBB) dysfunction is a hallmark of neurological conditions such as
multiple sclerosis (MS) and stroke. However, the molecular mechanisms underlying …
multiple sclerosis (MS) and stroke. However, the molecular mechanisms underlying …
Physiological roles of miR‐155
R Mashima - Immunology, 2015 - Wiley Online Library
Summary miR‐155 is involved in non‐coding microRNAs found in humans, mice and
chickens of which the sequence is conserved. Historically, miR‐155 was identified as a B …
chickens of which the sequence is conserved. Historically, miR‐155 was identified as a B …