Mycobacterium tuberculosis (Mtb) adhesin proteins are promising candidates for subunit
vaccine design. Multi-epitope Mtb vaccine and diagnostic candidates were designed using …

Objective Serum proteomic analysis of tuberculosis (TB) antigens to identify biomarkers
enabling discrimination of active TB (ATB) from latent TB infection (LTBI). Methods Serum …

Type I interferon (IFN) plays an important role in Mycobacterium tuberculosis persistence
and disease pathogenesis. M. tuberculosis has evolved a number of mechanisms to evade …

T uberculosis (TB) is one of the top 10 causes of death worldwide, and millions of people are
affected by contracting tuberculosis every year (1). The World Health Organization (WHO) …

Multi-stage tuberculosis (TB) vaccines composed of active-and dormancy-associated
antigens are promising to trigger the immune protection against all TB stages. However …

Ante-mortem diagnosis of caprine tuberculosis, as in other ruminant species, is a complex
process. Therefore, it is sometimes necessary to apply a combination of methods that …

Background A previous study demonstrated pleural fluid (PF) IgA immunodominance for the
fused MT10. 3: MPT64 protein in pleural tuberculosis (PLTB) cases. However, no clue on the …

Tuberculosis (TB) remains a serious threat in underdeveloped areas. Mycobacterium
tuberculosis curli pili (MTP), a virulence factor, is a potential biomarker for a reliable point of …

The 38 kDa protein is a major antigen of mycobacterium tuberculosis and has been widely
used in TB serodiagnosis, due to its highly sensitivity and specificity. Here we attempt to …

Background Diagnosis of tuberculosis (TB) is still difficult. The development of rapid and
sensitive laboratory tools for the diagnosis of tuberculosis is a priority. This study aimed to …