Ketamine: 50 years of modulating the mind
Ketamine was introduced into clinical practice in the 1960s and continues to be both
clinically useful and scientifically fascinating. With considerably diverse molecular targets …
clinically useful and scientifically fascinating. With considerably diverse molecular targets …
Perioperative intravenous ketamine for acute postoperative pain in adults
ECV Brinck, E Tiippana, M Heesen… - Cochrane Database …, 2018 - cochranelibrary.com
Background Inadequate pain management after surgery increases the risk of postoperative
complications and may predispose for chronic postsurgical pain. Perioperative ketamine …
complications and may predispose for chronic postsurgical pain. Perioperative ketamine …
Perioperative ketamine for postoperative pain management in patients with preoperative opioid intake: a systematic review and meta-analysis
CH Meyer-Frießem, E Lipke, S Weibel, P Kranke… - Journal of clinical …, 2022 - Elsevier
Study objective Postoperative pain management in opioid users remains challenging. The
perioperative administration of ketamine might lead to favourable pain outcomes in these …
perioperative administration of ketamine might lead to favourable pain outcomes in these …
[PDF][PDF] Ketamine added to morphine or hydromorphone patient-controlled analgesia for acute postoperative pain in adults: a systematic review and meta-analysis of …
Purpose To determine whether ketamine added to morphine or hydromorphone patient-
controlled analgesia (PCA) provides clinically relevant reductions in postoperative pain …
controlled analgesia (PCA) provides clinically relevant reductions in postoperative pain …
Expanding role of NMDA receptor antagonists in the management of pain
D Kreutzwiser, QA Tawfic - Cns Drugs, 2019 - Springer
Pain management is complex regardless of whether the pain is acute or chronic in nature or
non-cancer or cancer related. In addition, relatively few pain pharmacotherapy options with …
non-cancer or cancer related. In addition, relatively few pain pharmacotherapy options with …
Benefit and harm of adding ketamine to an opioid in a patient-controlled analgesia device for the control of postoperative pain: systematic review and meta-analyses of …
Ketamine is often added to opioids in patient-controlled analgesia devices. We tested
whether in surgical patients, ketamine added to an opioid patient–controlled analgesia …
whether in surgical patients, ketamine added to an opioid patient–controlled analgesia …
[HTML][HTML] Magnesium and ketamine gargle and postoperative sore throat
Background: Postoperative sore throat is one of the most common complications after
endotracheal intubation. Both Ketamine and magnesium can block N-methyl-D-aspartic acid …
endotracheal intubation. Both Ketamine and magnesium can block N-methyl-D-aspartic acid …
Ketamine–An Imperfect Wonder Drug?
T Magruder, M Isenhart, MV Striepe, A Mannisto… - Biochemical …, 2024 - Elsevier
Ketamine is a potent sedative and dissociative anesthetic agent that has been used
clinically for over 50 years since it was first developed in the 1960 s as an alternative to …
clinically for over 50 years since it was first developed in the 1960 s as an alternative to …
A comparative investigation of the analgesic effects of metamizole and paracetamol in rats
Background: This study investigated the effects of metamizole and paracetamol on pain and
oxidative stress induced by scalpel incision and carrageenan in rats. Materials and methods …
oxidative stress induced by scalpel incision and carrageenan in rats. Materials and methods …
Comparison of the effect of adding low-dose ketamine to dexmedetomidine and propofol on the quality of sedation and hemodynamic response in children during …
Background: As endoscopy is an invasive and painful procedure, it is necessary to use a
suitable sedative with a minimum dose, especially in children. Objectives: This study aimed …
suitable sedative with a minimum dose, especially in children. Objectives: This study aimed …