We propose a new paradigm for dense functional imaging of brain activity to surmount the
limitations of present methodologies. We term this approach" integrated neurophotonics"; it …

The study of electronic properties of materials at the nanoscale has unveiled physical laws
and generated materials such as nanoparticles, quantum dots, nanodiamonds …

The use of optogenetic stimulation to evoke neuronal activity in targeted neural populations—
enabled by opsins with fast kinetics, high sensitivity and cell-type and subcellular specificity …

Significance: Light-sheet fluorescence microscopy (LSFM) is a powerful technique for
highspeed volumetric functional imaging. However, in typical light-sheet microscopes, the …

Implantable image sensors have the potential to revolutionize neuroscience. Due to their
small form factor requirements; however, conventional filters and optics cannot be …

Optical neurotechnologies use light to interface with neurons and can monitor and
manipulate neural activity with high spatial-temporal precision over large cortical areas …

This article presents a high-detection rate single-photon avalanche diode (SPAD) imaging
chip designed for photon-sensing applications. The test chip includes two essential design …

Real-time monitoring of dynamic biological processes in the body is critical to understanding
disease progression and treatment response. These data, for instance, can help address the …

This paper presents a device for time-gated fluorescence imaging in the deep brain,
consisting of two on-chip laser diodes and 512 single-photon avalanche diodes (SPADs) …

Optical neurotechnologies use light to interface with neurons and can monitor and
manipulate neural activity with high spatial-temporal precision over large cortical extents …