Going beyond primary motor cortex to improve brain–computer interfaces
Brain–computer interfaces (BCIs) for movement restoration typically decode the user's intent
from neural activity in their primary motor cortex (M1) and use this information to enable …
from neural activity in their primary motor cortex (M1) and use this information to enable …
Preparatory activity and the expansive null-space
The study of the cortical control of movement experienced a conceptual shift over recent
decades, as the basic currency of understanding shifted from single-neuron tuning towards …
decades, as the basic currency of understanding shifted from single-neuron tuning towards …
Mice alternate between discrete strategies during perceptual decision-making
Classical models of perceptual decision-making assume that subjects use a single,
consistent strategy to form decisions, or that decision-making strategies evolve slowly over …
consistent strategy to form decisions, or that decision-making strategies evolve slowly over …
Slow drift of neural activity as a signature of impulsivity in macaque visual and prefrontal cortex
An animal's decision depends not only on incoming sensory evidence but also on its
fluctuating internal state. This state embodies multiple cognitive factors, such as arousal and …
fluctuating internal state. This state embodies multiple cognitive factors, such as arousal and …
Contribution of behavioural variability to representational drift
Neuronal responses to similar stimuli change dynamically over time, raising the question of
how internal representations can provide a stable substrate for neural coding. Recent work …
how internal representations can provide a stable substrate for neural coding. Recent work …
Learning leaves a memory trace in motor cortex
How are we able to learn new behaviors without disrupting previously learned ones? To
understand how the brain achieves this, we used a brain-computer interface (BCI) learning …
understand how the brain achieves this, we used a brain-computer interface (BCI) learning …
A neural basis of choking under pressure
Incentives tend to drive improvements in performance. But when incentives get too high, we
can" choke under pressure" and underperform right when it matters most. What neural …
can" choke under pressure" and underperform right when it matters most. What neural …
How learning unfolds in the brain: toward an optimization view
How do changes in the brain lead to learning? To answer this question, consider an artificial
neural network (ANN), where learning proceeds by optimizing a given objective or cost …
neural network (ANN), where learning proceeds by optimizing a given objective or cost …
Fundamental processes in sensorimotor learning: Reasoning, refinement, and retrieval
Motor learning is often viewed as a unitary process that operates outside of conscious
awareness. This perspective has led to the development of sophisticated models designed …
awareness. This perspective has led to the development of sophisticated models designed …
Nonlinear manifolds underlie neural population activity during behaviour
There is rich variety in the activity of single neurons recorded during behaviour. Yet, these
diverse single neuron responses can be well described by relatively few patterns of neural …
diverse single neuron responses can be well described by relatively few patterns of neural …