[HTML][HTML] Effectiveness and safety of immunotherapy in NSCLC patients with ECOG PS score≥ 2–systematic review and meta-analysis
Abstract Background Immune checkpoint inhibitors (ICIs) are standard of care in advanced
non-small cell lung cancer (NSCLC), however their status in patients with poor performance …
non-small cell lung cancer (NSCLC), however their status in patients with poor performance …
Ocular immune-related adverse events associated with immune checkpoint inhibitors in lung cancer
L Zhou, X Wei - Frontiers in Immunology, 2021 - frontiersin.org
Immune checkpoint inhibitors (ICIs) are novel immunotherapy-based drugs that have
become increasingly popular in the treatment of lung cancer. Researchers have recognized …
become increasingly popular in the treatment of lung cancer. Researchers have recognized …
Impact of patient age on clinical efficacy and toxicity of checkpoint inhibitor therapy
The addition of immune checkpoint inhibitors (ICIs) to the therapeutic armamentarium for
solid malignancies has resulted in unprecedented improvements in patient outcomes in …
solid malignancies has resulted in unprecedented improvements in patient outcomes in …
Aging, cancer, and antitumor immunity
H Ikeda, Y Togashi - International Journal of Clinical Oncology, 2022 - Springer
Aging leads to numerous changes that affect many components of the immune system,
called “immunosenescence”. Indeed, elderly individuals exhibit dysregulated immune …
called “immunosenescence”. Indeed, elderly individuals exhibit dysregulated immune …
[HTML][HTML] Impact of aging on immune-related adverse events generated by anti–programmed death (ligand) PD-(L) 1 therapies
C Baldini, PM Romano, AL Voisin, FX Danlos… - European Journal of …, 2020 - Elsevier
Background Aging is an important risk factor for cancers and is associated with poor
prognosis. Weakness of the immune system, also called immunosenescence may occur with …
prognosis. Weakness of the immune system, also called immunosenescence may occur with …
The effects of age and systemic metabolism on anti-tumor T cell responses
JM Drijvers, AH Sharpe, MC Haigis - Elife, 2020 - elifesciences.org
Average age and obesity prevalence are increasing globally. Both aging and obesity are
characterized by profound systemic metabolic and immunologic changes and are cancer …
characterized by profound systemic metabolic and immunologic changes and are cancer …
Immune checkpoint inhibitor‐related adverse events in lung cancer: Real‐world incidence and management practices of 1905 patients in China
Y Shi, J Fang, C Zhou, A Liu, Y Wang, Q Meng… - Thoracic …, 2022 - Wiley Online Library
Abstract Background Immune checkpoint inhibitors (ICIs) are the standard treatment for
advanced lung cancer, but immune‐related adverse events (irAEs) remain poorly …
advanced lung cancer, but immune‐related adverse events (irAEs) remain poorly …
The progress and confusion of anti-PD1/PD-L1 immunotherapy for patients with advanced non-small cell lung cancer
S Zhang, X Bai, F Shan - International Immunopharmacology, 2020 - Elsevier
Recently, immunotherapy has evolved into a true treatment modality with the approval of PD-
1 and PD-L1 inhibitors as the standard care for first-line treatment in patients with non-small …
1 and PD-L1 inhibitors as the standard care for first-line treatment in patients with non-small …
[HTML][HTML] Real world data in the era of Immune Checkpoint Inhibitors (ICIs): Increasing evidence and future applications in lung cancer
G Pasello, A Pavan, I Attili, A Bortolami… - Cancer treatment …, 2020 - Elsevier
Immune checkpoint inhibitors (ICIs) targeting programmed death 1 (PD-1) and PD-ligand 1
(PD-L1) quickly subverted the standard of treatment in Non-Small Cell Lung Cancer …
(PD-L1) quickly subverted the standard of treatment in Non-Small Cell Lung Cancer …
Age, sex, and specific gene mutations affect the effects of immune checkpoint inhibitors in colorectal cancer
The effect of age and sex on the predictive value of colorectal cancer (CRC) patients treated
with immune checkpoint inhibitors (ICIs) has been controversial, and the effect of specific …
with immune checkpoint inhibitors (ICIs) has been controversial, and the effect of specific …