Biomaterials and bioactive natural products from marine invertebrates: From basic research to innovative applications

G Romano, M Almeida, A Varela Coelho, A Cutignano… - Marine Drugs, 2022 - mdpi.com
Aquatic invertebrates are a major source of biomaterials and bioactive natural products that
can find applications as pharmaceutics, nutraceutics, cosmetics, antibiotics, antifouling …

Marine natural products

JW Blunt, BR Copp, RA Keyzers, MHG Munro… - Natural product …, 2013 - pubs.rsc.org
Covering: 2011. Previous review: Nat. Prod. Rep., 2012, 29, 144–222. This review covers
the literature published in 2011 for marine natural products, with 870 citations (558 for the …

Electrophilic Halospirocyclization of N-Benzylacrylamides to Access 4-Halomethyl-2-azaspiro[4.5]decanes

Z Zhang, W Zhang, ZW Hou, P Li… - The Journal of Organic …, 2023 - ACS Publications
An electrophilic spirocyclization of N-benzylacrylamides with N-halosuccinimides (NXS) as
the halogenating reagents has been developed. This reaction is carried out at room …

Electrochemical electrophilic bromination/spirocyclization of N-benzyl-acrylamides to brominated 2-azaspiro [4.5] decanes

Z Zhang, ZW Hou, H Chen, P Li, L Wang - Green Chemistry, 2023 - pubs.rsc.org
An electrochemical electrophilic bromination/spirocyclization of N-benzyl-acrylamides with 2-
bromoethan-1-ol as the brominating reagent has been developed. The paired electrolysis …

Marine natural products

JW Blunt, BR Copp, MHG Munro, PT Northcote… - Natural product …, 2005 - pubs.rsc.org
Covering: 2003. Previous review: Nat. Prod. Rep., 2004, 21, 1 This review covers the
literature published in 2003 for marine natural products, with 619 citations (413 for the …

Photo-induced spirocyclization of biaryl ynones with ammonium thiocyanate: access to thiocyanate-featured spiro [5, 5] trienones

S Chen, Q Yan, J Fan, C Guo, L Li, ZQ Liu, Z Li - Green Chemistry, 2023 - pubs.rsc.org
Photo-promoted mild tandem 6-exo-trig spirocyclization of biaryl ynones with ammonium
thiocyanate has been developed to access thiocyanate-containing spiro [5, 5] trienones with …

Electrochemical Annulation–Iodosulfonylation of 1,5-Enyne-containing para-Quinone Methides (p-QMs) to Access (E)-Spiroindenes

HD Zuo, WJ Hao, CF Zhu, C Guo, SJ Tu, B Jiang - Organic Letters, 2020 - ACS Publications
A new electrochemical three-component annulation–iodosulfonylation of 1, 5-enyne-
containing para-quinone methides (p-QMs) has been established by using available …

Radical Three-Component Nitro Spiro-Cyclization of Unsaturated Sulfonamides/Amides to Access NO2-Featured 4-Azaspiro[4.5]decanes

C Guo, L Li, Q Yan, J Chen, ZQ Liu, QX Li, SF Ni… - Organic …, 2024 - ACS Publications
Free radical three-component nitration/spirocyclization of unsaturated sulfonamides/amides
with tert-butyl nitrite was developed for the construction of diverse NO2-revised 4-azaspiro …

A metalloenzyme platform for catalytic asymmetric radical dearomatization

W Fu, Y Fu, Y Zhao, H Wang, P Liu, Y Yang - Nature Chemistry, 2024 - nature.com
Catalytic asymmetric dearomatization represents a powerful means to convert flat aromatic
compounds into stereochemically well-defined three-dimensional molecular scaffolds. Using …

Synthesis of polychloromethylated and halogenated spiro [5, 5] trienones via dearomative spirocyclization of biaryl ynones

JN Li, ZJ Li, LY Shen, P Li, Y Zhang… - Organic & Biomolecular …, 2022 - pubs.rsc.org
We disclosed a selective polychloromethylation and halogenation reaction of alkynes via a
radical addition/spirocyclization cascade sequence, in which polyhaloalkanes were used as …