Lysophosphatidic acid (LPA) is one of the simplest glycerophospholipids with one fatty acid
chain and a phosphate group as a polar head. Although LPA had been viewed just as a …

Lysophosphatidylcholine (LPC) and lysophosphatidic acid (LPA), the most prominent
lysoglycerophospholipids, are emerging as a novel class of inflammatory lipids, joining …

Autotaxin (ATX) is a secreted glycoprotein and functions as a key enzyme to produce
extracellular lysophosphatidic acid (LPA). LPA interacts with at least six G protein-coupled …

Lysophosphatidic acid (LPA) is a pleiotropic lipid molecule with potent effects on cell growth
and motility. Major progress has been made in recent years in deciphering the mechanisms …

Lysophosphatidic acid (LPA) is a ubiquitous lysophospholipid and one of the main
membrane‐derived lipid signaling molecules. LPA acts as an autocrine/paracrine …

Lipid phosphate phosphatases (LPPs) are a group of enzymes that belong to a
phosphatase/phosphotransferase family. Mammalian LPPs consist of three isoforms: LPP1 …

Autotaxin (ATX) is a secreted nucleotide pyrophosphatase/phosphodiesterase that functions
as a lysophospholipase D to produce the lipid mediator lysophosphatidic acid (LPA), a …

Lipid phosphate phosphatases (LPPs) regulate cell signaling by modifying the
concentrations of lipid phosphates versus their dephosphorylated products. The ecto-activity …

Autotaxin is a secreted enzyme that produces most of the extracellular lysophosphatidate
from lysophosphatidylcholine, the most abundant phospholipid in blood plasma …

Autotaxin (ATX) is a member of the ectonucleotide pyrophosphate/phosphodiesterase
(ENPP) family; it is encoded by the ENPP2 gene. ATX is a secreted glycoprotein and …