From phytocannabinoids to cannabinoid receptors and endocannabinoids: pleiotropic physiological and pathological roles through complex pharmacology

A Ligresti, L De Petrocellis… - Physiological …, 2016 - journals.physiology.org
Apart from having been used and misused for at least four millennia for, among others,
recreational and medicinal purposes, the cannabis plant and its most peculiar chemical …

Anti-cancer potential of cannabinoids, terpenes, and flavonoids present in cannabis

AM Tomko, EG Whynot, LD Ellis, DJ Dupré - Cancers, 2020 - mdpi.com
In recent years, and even more since its legalization in several jurisdictions, cannabis and
the endocannabinoid system have received an increasing amount of interest related to their …

Medicinal properties of cannabinoids, terpenes, and flavonoids in cannabis, and benefits in migraine, headache, and pain: an update on current evidence and …

EP Baron - Headache: The Journal of Head and Face Pain, 2018 - Wiley Online Library
Background Comprehensive literature reviews of historical perspectives and evidence
supporting cannabis/cannabinoids in the treatment of pain, including migraine and …

Towards the use of cannabinoids as antitumour agents

G Velasco, C Sánchez, M Guzmán - Nature Reviews Cancer, 2012 - nature.com
Various reports have shown that cannabinoids (the active components of marijuana and
their derivatives) can reduce tumour growth and progression in animal models of cancer, in …

Anticancer mechanisms of cannabinoids

G Velasco, C Sánchez, M Guzmán - Current Oncology, 2016 - mdpi.com
In addition to the well-known palliative effects of cannabinoids on some cancer-associated
symptoms, a large body of evidence shows that these molecules can decrease tumour …

Cannabinoids in the landscape of cancer

N Mangal, S Erridge, N Habib, A Sadanandam… - Journal of cancer …, 2021 - Springer
Introduction Cannabinoids are a group of terpenophenolic compounds derived from the
Cannabis sativa L. plant. There is a growing body of evidence from cell culture and animal …

Comprehensive review of medicinal marijuana, cannabinoids, and therapeutic implications in medicine and headache: what a long strange trip it's been…

EP Baron - Headache: The Journal of Head and Face Pain, 2015 - Wiley Online Library
Background The use of cannabis, or marijuana, for medicinal purposes is deeply rooted
though history, dating back to ancient times. It once held a prominent position in the history …

The current state and future perspectives of cannabinoids in cancer biology

P Śledziński, J Zeyland, R Słomski… - Cancer medicine, 2018 - Wiley Online Library
To date, cannabinoids have been allowed in the palliative medicine due to their analgesic
and antiemetic effects, but increasing number of preclinical studies indicates their anticancer …

[HTML][HTML] Cannabinoids as therapeutic agents in cancer: current status and future implications

B Chakravarti, J Ravi, RK Ganju - Oncotarget, 2014 - ncbi.nlm.nih.gov
The pharmacological importance of cannabinoids has been in study for several years.
Cannabinoids comprise of (a) the active compounds of the Cannabis sativa plant,(b) …

Cannabinoids as anticancer therapeutic agents

O Kovalchuk, I Kovalchuk - Cell Cycle, 2020 - Taylor & Francis
The recent announcement of marijuana legalization in Canada spiked many discussions
about potential health benefits of Cannabis sativa. Cannabinoids are active chemical …