Role of polyphenols in combating Type 2 Diabetes and insulin resistance

M Shahwan, F Alhumaydhi, GM Ashraf… - International journal of …, 2022 - Elsevier
Compromised carbohydrate metabolism leading to hyperglycemia is the primary metabolic
disorder of non-insulin-dependent diabetes mellitus. Reformed digestion and altered …

Healthy effects of plant polyphenols: molecular mechanisms

M Leri, M Scuto, ML Ontario, V Calabrese… - International journal of …, 2020 - mdpi.com
The increasing extension in life expectancy of human beings in developed countries is
accompanied by a progressively greater rate of degenerative diseases associated with …

The central role of glucokinase in glucose homeostasis: a perspective 50 years after demonstrating the presence of the enzyme in islets of Langerhans

FM Matschinsky, DF Wilson - Frontiers in physiology, 2019 - frontiersin.org
It is hypothesized that glucokinase (GCK) is the glucose sensor not only for regulation of
insulin release by pancreatic β-cells, but also for the rest of the cells that contribute to …

Polyphenols and glycemic control

Y Kim, JB Keogh, PM Clifton - Nutrients, 2016 - mdpi.com
Growing evidence from animal studies supports the anti-diabetic properties of some dietary
polyphenols, suggesting that dietary polyphenols could be one dietary therapy for the …

Probiotics, prebiotics, synbiotics and insulin sensitivity

YA Kim, JB Keogh, PM Clifton - Nutrition research reviews, 2018 - cambridge.org
Animal studies indicate that the composition of gut microbiota may be involved in the
progression of insulin resistance to type 2 diabetes. Probiotics and/or prebiotics could be a …

Utilisation of dietary carbohydrates in farmed fishes: new insights on influencing factors, biological limitations and future strategies

BS Kamalam, F Medale, S Panserat - Aquaculture, 2017 - Elsevier
Carbohydrates are the most abundant class of energy yielding nutrients which is
economically indispensable in commercial fish feed formulations. But, the ability of farmed …

Emerging role of the brain in the homeostatic regulation of energy and glucose metabolism

E Roh, DK Song, MS Kim - Experimental & molecular medicine, 2016 - nature.com
Accumulated evidence from genetic animal models suggests that the brain, particularly the
hypothalamus, has a key role in the homeostatic regulation of energy and glucose …

The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress

RJ Shaw, M Kosmatka, N Bardeesy, RL Hurley… - Proceedings of the …, 2004 - pnas.org
AMP-activated protein kinase (AMPK) is a highly conserved sensor of cellular energy status
found in all eukaryotic cells. AMPK is activated by stimuli that increase the cellular AMP/ATP …

CD36 promotes NLRP3 inflammasome activation via the mtROS pathway in renal tubular epithelial cells of diabetic kidneys

Y Hou, Q Wang, B Han, Y Chen, X Qiao, L Wang - Cell death & disease, 2021 - nature.com
Tubulointerstitial inflammation plays a key role in the pathogenesis of diabetic nephropathy
(DN). Interleukin-1β (IL-1β) is the key proinflammatory cytokine associated with …

[HTML][HTML] The effects of aerobic, resistance, and combined exercise on metabolic control, inflammatory markers, adipocytokines, and muscle insulin signaling in patients …

MLMP Jorge, VN de Oliveira, NM Resende, LF Paraiso… - Metabolism, 2011 - Elsevier
The purpose of this study was to compare the effects of 3 different modalities of exercise on
metabolic control, insulin resistance, inflammatory markers, adipocytokines, and tissue …