Pathogenic mechanisms of post-acute sequelae of SARS-CoV-2 infection (PASC)

ZA Sherif, CR Gomez, TJ Connors, TJ Henrich… - Elife, 2023 - elifesciences.org
COVID-19, with persistent and new onset of symptoms such as fatigue, post-exertional
malaise, and cognitive dysfunction that last for months and impact everyday functioning, is …

Post-COVID syndrome: an insight on its pathogenesis

HC Maltezou, A Pavli, A Tsakris - Vaccines, 2021 - mdpi.com
Post-COVID syndrome is increasingly recognized as a new clinical entity in the context of
SARS-CoV-2 infection. Symptoms persisting for more than three weeks after the diagnosis of …

Persistent endotheliopathy in the pathogenesis of long COVID syndrome

H Fogarty, L Townsend, H Morrin… - … of thrombosis and …, 2021 - Wiley Online Library
Background Persistent symptoms including breathlessness, fatigue, and decreased exercise
tolerance have been reported in patients after acute SARS‐CoV‐2 infection. The biological …

Long COVID-19 syndrome: a comprehensive review of its effect on various organ systems and recommendation on rehabilitation plans

Z Yan, M Yang, CL Lai - Biomedicines, 2021 - mdpi.com
The majority of people infected with SARS-CoV-2 fully recovered within a few weeks.
However, a considerable number of patients of different ages still suffer from long-lasting …

Long COVID and the cardiovascular system—elucidating causes and cellular mechanisms in order to develop targeted diagnostic and therapeutic strategies: a joint …

M Gyöngyösi, P Alcaide, FW Asselbergs… - Cardiovascular …, 2023 - academic.oup.com
Long COVID has become a world-wide, non-communicable epidemic, caused by long-
lasting multiorgan symptoms that endure for weeks or months after SARS-CoV-2 infection …

Vasculopathy in COVID-19

R Flaumenhaft, K Enjyoji… - Blood, The Journal of the …, 2022 - ashpublications.org
COVID-19 is a primary respiratory illness that is frequently complicated by systemic
involvement of the vasculature. Vascular involvement leads to an array of complications …

[HTML][HTML] ESCMID rapid guidelines for assessment and management of long COVID

D Yelin, CD Moschopoulos, I Margalit… - Clinical Microbiology …, 2022 - Elsevier
Scope The aim of these guidelines is to provide evidence-based recommendations for the
assessment and management of individuals with persistent symptoms after acute COVID-19 …

A central role for amyloid fibrin microclots in long COVID/PASC: origins and therapeutic implications

DB Kell, GJ Laubscher, E Pretorius - Biochemical Journal, 2022 - portlandpress.com
Post-acute sequelae of COVID (PASC), usually referred to as 'Long COVID'(a phenotype of
COVID-19), is a relatively frequent consequence of SARS-CoV-2 infection, in which …

Incomplete systemic recovery and metabolic phenoreversion in post-acute-phase nonhospitalized COVID-19 patients: implications for assessment of post-acute …

E Holmes, J Wist, R Masuda, S Lodge… - Journal of proteome …, 2021 - ACS Publications
We present a multivariate metaboty** approach to assess the functional recovery of
nonhospitalized COVID-19 patients and the possible biochemical sequelae of “Post-Acute …

COVID-19 and the vasculature: current aspects and long-term consequences

B Martinez-Salazar, M Holwerda, C Stuedle… - Frontiers in cell and …, 2022 - frontiersin.org
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) was first identified in
December 2019 as a novel respiratory pathogen and is the causative agent of Corona Virus …