The extracellular matrix (ECM) is the complex meshwork of proteins and glycans that forms
the scaffold that surrounds and supports cells. It exerts key roles in all aspects of metazoan …

Rotator cuff tears are the most common upper extremity condition seen by primary care and
orthopaedic surgeons, with a spectrum ranging from tendinopathy to full-thickness tears with …

Tissues are dynamically shaped by bidirectional communication between resident cells and
the extracellular matrix (ECM) through cell-matrix interactions and ECM remodelling …

Collagen is the oldest and most abundant extracellular matrix protein that has found many
applications in food, cosmetic, pharmaceutical, and biomedical industries. First, an overview …

Synthetic bone substitute materials (BSMs) are becoming the general trend, replacing
autologous grafting for bone tissue engineering (BTE) in orthopedic research and clinical …

Periostin (POSTN), a member of the matricellular protein family, is a secreted adhesion-
related protein produced in the periosteum and periodontal ligaments. Matricellular proteins …

A variety of soft, hydrogel-like materials with sophisticated micro-and nanoengineered
ordered structures that offer excellent functionalities exist in nature. Conventional synthetic …

Cancer-associated fibroblasts (CAFs) are a prominent stromal cell type in solid tumors and
molecules secreted by CAFs play an important role in tumor progression and metastasis …

Membrane technology has had a continue growth for the last 40 years. The forecast is that
the membrane market will reach US $10.8 billion by the end of 2019. Unfortunately, it is also …

Natural structural materials (such as tendons and ligaments) are comprised of multiscale
hierarchical architectures, with dimensions ranging from nano‐to macroscale, which are …