Wound healing: cellular mechanisms and pathological outcomes

HN Wilkinson, MJ Hardman - Open biology, 2020 - royalsocietypublishing.org
Wound healing is a complex, dynamic process supported by a myriad of cellular events that
must be tightly coordinated to efficiently repair damaged tissue. Derangement in wound …

Minoxidil and its use in hair disorders: a review

P Suchonwanit, S Thammarucha… - Drug design …, 2019 - Taylor & Francis
Minoxidil was first introduced as an antihypertensive medication and the discovery of its
common adverse event, hypertrichosis, led to the development of a topical formulation for …

Microneedle-mediated vaccination: innovation and translation

T Sheng, B Luo, W Zhang, X Ge, J Yu, Y Zhang… - Advanced drug delivery …, 2021 - Elsevier
Vaccine administration by subcutaneous or intramuscular injection is the most commonly
prescribed route for inoculation, however, it is often associated with some deficiencies such …

Advances in transdermal insulin delivery

Y Zhang, J Yu, AR Kahkoska, J Wang, JB Buse… - Advanced drug delivery …, 2019 - Elsevier
Insulin therapy is necessary to regulate blood glucose levels for people with type 1 diabetes
and commonly used in advanced type 2 diabetes. Although subcutaneous insulin …

Degradable lipid nanoparticles with predictable in vivo siRNA delivery activity

KA Whitehead, JR Dorkin, AJ Vegas, PH Chang… - Nature …, 2014 - nature.com
One of the most significant challenges in the development of clinically viable delivery
systems for RNA interference therapeutics is to understand how molecular structures …

[HTML][HTML] The immunology of the porcine skin and its value as a model for human skin

A Summerfield, F Meurens, ME Ricklin - Molecular immunology, 2015 - Elsevier
The porcine skin has striking similarities to the human skin in terms of general structure,
thickness, hair follicle content, pigmentation, collagen and lipid composition. This has been …

Evaluation of skin absorption of drugs from topical and transdermal formulations

ALM Ruela, AG Perissinato, MES Lino… - Brazilian journal of …, 2016 - SciELO Brasil
The skin barrier function has been attributed to the stratum corneum and represents a major
challenge in clinical practice pertaining to cutaneous administration of drugs. Despite this, a …

Essential oils and their constituents as skin penetration enhancer for transdermal drug delivery: a review

A Herman, AP Herman - Journal of Pharmacy and …, 2015 - academic.oup.com
Objectives In this paper, we focused on essential oils and their constituents as skin
penetration enhancers for transdermal drug delivery, mechanism of their action as well as …

Isolation of industrial important bioactive compounds from microalgae

V Balasubramaniam, RDN Gunasegavan, S Mustar… - Molecules, 2021 - mdpi.com
Microalgae are known as a rich source of bioactive compounds which exhibit different
biological activities. Increased demand for sustainable biomass for production of important …

Topical and cutaneous delivery using nanosystems

MS Roberts, Y Mohammed, MN Pastore… - Journal of controlled …, 2017 - Elsevier
The goal of topical and cutaneous delivery is to deliver therapeutic and other substances to
a desired target site in the skin at appropriate doses to achieve a safe and efficacious …