Tumor progression involves invasion, migration, metabolism, autophagy, exosome
secretion, and drug resistance. Cargos transported by membrane vesicle trafficking underlie …

Lipid droplets (LDs) are endoplasmic reticulum–derived organelles that consist of a core of
neutral lipids encircled by a phospholipid monolayer decorated with proteins. As hubs of …

Parkinson's disease (PD) is a complex and progressive neurodegenerative disorder with a
prevalence of approximately 0.5–1% among those aged 65–70 years. Although most of its …

Non-alcoholic fatty liver disease (NAFLD) is a chronic liver disease characterized by lipid
accumulation in hepatocytes in the absence of excessive alcohol consumption. The global …

Metabolic dysfunction-associated steatotic liver disease (MASLD) originates from a
homeostatic imbalance in hepatic lipid metabolism. Increased fat deposition in the liver of …

Gastric cancer (GC) is a tumor with high incidence and lack of early diagnostic markers. The
aim of this study was to explore novel regulatory circular RNAs (circRNAs) in GC and their …

Lipophagy is a central cellular process for providing the cell with a readily utilized, high
energy source of neutral lipids. Since its discovery over a decade ago, we are just starting to …

The liver is the key organ involved in lipid metabolism and transport. Excessive lipid
accumulation due to dysregulated lipid metabolism predisposes the liver to steatosis …

Genetic alterations in the LRRK2 gene, encoding leucine-rich repeat kinase 2, are a
common risk factor for Parkinson's disease. How LRRK2 alterations lead to cell pathology is …

Growing evidence has indicated that the long noncoding RNA (lncRNA) CYTOR is involved
in the initiation and progression of malignancies, including gastric cancer. Nevertheless, the …