Experimental and theoretical studies of a thiourea derivative: 1-(4-chloro-benzoyl)-3-(2-trifluoromethyl-phenyl) thiourea
A Alizada, H Arslan - Journal of Molecular Structure, 2023 - Elsevier
Abstract The 1-(4-chloro-benzoyl)-3-(2-trifluoromethyl-phenyl) thiourea compound was
synthesized by a two-step reaction and a single crystal of it was obtained by recrystallization …
synthesized by a two-step reaction and a single crystal of it was obtained by recrystallization …
9, 10-Anthraquinone dithiocarbamates as potential pharmaceutical substances with pleiotropic actions: Computerized prediction of biological activity and …
The pleiotropic pharmacological actions of 9, 10-anthraquinone dithiocarbamates were
studied. The Way2Drug web portal was used to establish that cytotoxic, antiviral, and …
studied. The Way2Drug web portal was used to establish that cytotoxic, antiviral, and …
Anthra[1,2-d][1,2,3]triazine-4,7,12(3H)-triones as a New Class of Antistaphylococcal Agents: Synthesis and Biological Evaluation
The development and spread of resistance of human pathogenic bacteria to the action of
commonly used antibacterial drugs is one of the key problems in modern medicine. One of …
commonly used antibacterial drugs is one of the key problems in modern medicine. One of …
TTF1 suppresses neuroblastoma growth and induces neuroblastoma differentiation by targeting TrkA and the miR-204/TrkB axis
Neuroblastoma (NB) is the most common extracranial malignant solid tumor in children. We
found that TTF1, TrkA, and miR-204 were lowly expressed, whereas TrkB was highly …
found that TTF1, TrkA, and miR-204 were lowly expressed, whereas TrkB was highly …
Exploiting activity cliffs for building pharmacophore models and comparison with other pharmacophore generation methods: sphingosine kinase 1 as case study
Activity cliffs (ACs) are defined as closely analogous compounds of significant affinity
discrepancies against certain biotarget. In this paper we propose to use AC pair (s) for …
discrepancies against certain biotarget. In this paper we propose to use AC pair (s) for …
[PDF][PDF] N–((2–Acetylphenyl) carbamothioyl) benzamide: Synthesis, crystal structure analysis, and theoretical studies
A Oztaslar, H Arslan - Karbala International Journal of Modern Science, 2023 - iasj.net
Abstract N–((2–Acetylphenyl) carbamothioyl) benzamide has been synthesized and
characterized. The molecular conformation of the investigated compound is stabilized by …
characterized. The molecular conformation of the investigated compound is stabilized by …
Computer-aided prediction and cytotoxicity evaluation of dithiocarbamates of 9, 10-anthracenedione as new anticancer agents
Anticancer activity as an associated action for a series of dithiocarbamates of 9, 10-
anthracenedione was predicted using the PASS computer program and analysed with …
anthracenedione was predicted using the PASS computer program and analysed with …
Arsenic trioxide induces cell cycle arrest and affects Trk receptor expression in human neuroblastoma SK-N-SH cells
X **ong, Y Li, L Liu, K Qi, C Zhang, Y Chen, J Fang - Biological Research, 2018 - Springer
Abstract Background Arsenic trioxide (As 2 O 3), a drug that has been used in China for
approximately two thousand years, induces cell death in a variety of cancer cell types …
approximately two thousand years, induces cell death in a variety of cancer cell types …
[PDF][PDF] Synthesis and antimicrobial activity of nitrogen-containing anthraquinone derivatives
New substituted anthraquinones with amino derivations fragments were synthesized
through the substitution of bromine atom by different amines using the Ullmann coupling …
through the substitution of bromine atom by different amines using the Ullmann coupling …
[PDF][PDF] Synthesis and study of antimicrobial activity of 2-dithiocarbamate-N-(9, 10-dioxo-9, 10-dihydroanthracenyl) acetamides
The global emergence and dissemination of multidrug-resistant fungal and bacterial
pathogens is a serious public health threat. The development of novel highly active …
pathogens is a serious public health threat. The development of novel highly active …