Signal pathways of melanoma and targeted therapy
W Guo, H Wang, C Li - Signal transduction and targeted therapy, 2021 - nature.com
Melanoma is the most lethal skin cancer that originates from the malignant transformation of
melanocytes. Although melanoma has long been regarded as a cancerous malignancy with …
melanocytes. Although melanoma has long been regarded as a cancerous malignancy with …
OncomiR or tumor suppressor? The duplicity of microRNAs in cancer
MicroRNAs (miRNA) are short, noncoding RNAs whose dysregulation has been implicated
in most, if not all, cancers. They regulate gene expression by suppressing mRNA translation …
in most, if not all, cancers. They regulate gene expression by suppressing mRNA translation …
Unraveling the crosstalk between melanoma and immune cells in the tumor microenvironment
Cutaneous melanoma is the most common skin cancer with an incidence that has been
rapidly increasing in the past decades. Melanomas are among the most immunogenic …
rapidly increasing in the past decades. Melanomas are among the most immunogenic …
A systems biology approach identifies FUT8 as a driver of melanoma metastasis
Association of aberrant glycosylation with melanoma progression is based mainly on
analyses of cell lines. Here we present a systems-based study of glycomic changes and …
analyses of cell lines. Here we present a systems-based study of glycomic changes and …
Control of mucin-type O-glycosylation: a classification of the polypeptide GalNAc-transferase gene family
Glycosylation of proteins is an essential process in all eukaryotes and a great diversity in
types of protein glycosylation exists in animals, plants and microorganisms. Mucin-type O …
types of protein glycosylation exists in animals, plants and microorganisms. Mucin-type O …
Epigenetic regulation in human melanoma: past and future
The development and progression of melanoma have been attributed to independent or
combined genetic and epigenetic events. There has been remarkable progress in …
combined genetic and epigenetic events. There has been remarkable progress in …
Advances in bioactivity of microRNAs of plant-derived exosome-like nanoparticles and milk-derived extracellular vesicles
D Li, X Yao, J Yue, Y Fang, G Cao… - Journal of Agricultural …, 2022 - ACS Publications
MicroRNA (miRNA) is a class of small noncoding RNA involved in physiological and
pathological processes via the regulation of gene expression. Naked miRNAs are unstable …
pathological processes via the regulation of gene expression. Naked miRNAs are unstable …
Molecular networks that regulate cancer metastasis
Tumor metastases are responsible for approximately 90% of all cancer-related deaths.
Although many patients can be cured, in the US and UK, cancer still causes 730,000 deaths …
Although many patients can be cured, in the US and UK, cancer still causes 730,000 deaths …
Immune-related microRNAs are abundant in breast milk exosomes
Breast milk is a complex liquid rich in immunological components that affect the
development of the infant's immune system. Exosomes are membranous vesicles of …
development of the infant's immune system. Exosomes are membranous vesicles of …
MicroRNAs in breastmilk and the lactating breast: potential immunoprotectors and developmental regulators for the infant and the mother
Human milk (HM) is the optimal source of nutrition, protection and developmental
programming for infants. It is species-specific and consists of various bioactive components …
programming for infants. It is species-specific and consists of various bioactive components …