The evolution of SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused millions of
deaths and substantial morbidity worldwide. Intense scientific effort to understand the …
deaths and substantial morbidity worldwide. Intense scientific effort to understand the …
The humoral response and antibodies against SARS-CoV-2 infection
Two and a half years into the COVID-19 pandemic, we have gained many insights into the
human antibody response to the causative SARS-CoV-2 virus. In this Review, we …
human antibody response to the causative SARS-CoV-2 virus. In this Review, we …
Rational identification of potent and broad sarbecovirus-neutralizing antibody cocktails from SARS convalescents
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron sublineages have
escaped most receptor-binding domain (RBD)-targeting therapeutic neutralizing antibodies …
escaped most receptor-binding domain (RBD)-targeting therapeutic neutralizing antibodies …
The mRNA vaccine revolution: COVID-19 has launched the future of vaccinology
During the COVID-19 pandemic, mRNA (mRNA) vaccines emerged as leading vaccine
candidates in a record time. Nonreplicating mRNA (NRM) and self-amplifying mRNA (SAM) …
candidates in a record time. Nonreplicating mRNA (NRM) and self-amplifying mRNA (SAM) …
[HTML][HTML] Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause deadly disease
Pan-betacoronavirus neutralizing antibodies may hold the key to develo** broadly
protective vaccines against novel pandemic coronaviruses and to more effectively respond …
protective vaccines against novel pandemic coronaviruses and to more effectively respond …
A MERS-CoV antibody neutralizes a pre-emerging group 2c bat coronavirus
The repeated emergence of zoonotic human betacoronaviruses (β-CoVs) dictates the need
for broad therapeutics and conserved epitope targets for countermeasure design. Middle …
for broad therapeutics and conserved epitope targets for countermeasure design. Middle …
A broad and potent neutralization epitope in SARS-related coronaviruses
Many neutralizing antibodies (nAbs) elicited to ancestral severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) through natural infection and vaccination have reduced …
coronavirus 2 (SARS-CoV-2) through natural infection and vaccination have reduced …
Broadly neutralizing and protective nanobodies against SARS-CoV-2 Omicron subvariants BA. 1, BA. 2, and BA. 4/5 and diverse sarbecoviruses
Abstract As SARS-CoV-2 Omicron and other variants of concern (VOCs) continue spreading
worldwide, development of antibodies and vaccines to confer broad and protective activity is …
worldwide, development of antibodies and vaccines to confer broad and protective activity is …
Structural basis for a conserved neutralization epitope on the receptor-binding domain of SARS-CoV-2
KYA Huang, X Chen, A Mohapatra, HTV Nguyen… - Nature …, 2023 - nature.com
Antibody-mediated immunity plays a crucial role in protection against SARS-CoV-2 infection.
We isolated a panel of neutralizing anti-receptor-binding domain (RBD) antibodies elicited …
We isolated a panel of neutralizing anti-receptor-binding domain (RBD) antibodies elicited …
Multivalent S2-based vaccines provide broad protection against SARS-CoV-2 variants of concern and pangolin coronaviruses
Background The COVID-19 pandemic continues to cause morbidity and mortality worldwide.
Most approved COVID-19 vaccines generate a neutralizing antibody response that primarily …
Most approved COVID-19 vaccines generate a neutralizing antibody response that primarily …