Shining new light on biological systems: luminescent transition metal complexes for bioimaging and biosensing applications

LCC Lee, KKW Lo - Chemical Reviews, 2024 - ACS Publications
Luminescence imaging is a powerful and versatile technique for investigating cell
physiology and pathology in living systems, making significant contributions to life science …

Detection of hypoxia in cancer models: significance, challenges, and advances

I Godet, S Doctorman, F Wu, DM Gilkes - Cells, 2022 - mdpi.com
The rapid proliferation of cancer cells combined with deficient vessels cause regions of
nutrient and O2 deprivation in solid tumors. Some cancer cells can adapt to these extreme …

Dual-mode tumor imaging using probes that are responsive to hypoxia-induced pathological conditions

SAAS Subasinghe, RG Pautler, MAH Samee… - Biosensors, 2022 - mdpi.com
Hypoxia in solid tumors is associated with poor prognosis, increased aggressiveness, and
strong resistance to therapeutics, making accurate monitoring of hypoxia important. Several …

Cherenkov luminescence in tumor diagnosis and treatment: A review

X Wang, L Li, J Li, P Wang, J Lang, Y Yang - Photonics, 2022 - mdpi.com
Malignant tumors rank as a leading cause of death worldwide. Accurate diagnosis and
advanced treatment options are crucial to win battle against tumors. In recent years …

[HTML][HTML] Novel Biophotonic Techniques for Phototherapy Enhancement: Cerenkov Radiation as a Bridge between Ionizing and Non-Ionizing Radiation Treatment

E Spyratou, K Kokkinogoulis, G Tsigaridas… - Journal of …, 2023 - mdpi.com
In oncology, tremendous research has been conducted on the use of alternative minimally
invasive techniques for cancer treatment and diagnosis. The use of biophotonic techniques …

A radiation biological analysis of the oxygen effect as a possible mechanism in FLASH

HM Swartz, PJ Hoopes, DJ Gladstone… - Oxygen Transport to …, 2022 - Springer
The delivery of radiation at an ultra-high dose rate (FLASH) is an important new approach to
radiotherapy (RT) that appears to be able to improve the therapeutic ratio by diminishing …

Review of Tissue Oxygenation Sensing During Radiotherapy Based Upon Cherenkov-Excited Luminescence Imaging

BW Pogue, X Cao, HM Swartz… - Applied Magnetic …, 2021 - Springer
Oxygen sensing with light has been develo** for many decades using injectable
molecules called Oxyphors, which are pegylated, dendrimer-encapsulated …