Congenital Diaphragmatic hernia (CDH) is a condition characterized by a defect in the
diaphragm leading to protrusion of abdominal contents into the thoracic cavity interfering …

Sepsis or serious infection within the first four weeks of life kills greater than 1 million
newborns globally every year1. The attack rate for neonatal sepsis is variable (from< 1% to> …

Twenty percent of very-low-birth-weight (< 1500 g) preterm infants experience a serious
systemic infection, and despite advances in neonatal intensive care and antimicrobials …

Hemodynamic disturbance in the sick neonate is common, highly diverse in underlying
pathophysiology and dynamic. Dysregulated systemic and cerebral blood flow is …

Background. Maintaining adequate organ blood flow is the target of vasopressor treatment,
but the impact of these measures on cerebral perfusion has not yet been evaluated …

Objective. To assess the effectiveness of a “stress dose” of hydrocortisone for rescue
treatment of refractory hypotension and adrenocortical insufficiency of prematurity in very …

Cortisol release in the face of illness or stress is vital for survival. Relative adrenal
insufficiency occurs when a patient's cortisol response is inadequate for the degree of illness …

Objectives. Hypotension occurs commonly among preterm neonates, but its cause and
consequences remain unclear. Secondary data analyses from the NEOPAIN trial identified …

Methods: We performed systematic reviews of the literature in order to determine which
preterm infants may benefit from treatment with interventions to elevate blood pressure (BP) …

BACKGROUND. Low cortisol concentrations in premature infants have been correlated with
increased severity of illness, hypotension, mortality, and development of bronchopulmonary …