The emergence of human induced pluripotent stem cells (hiPSCs) and efficient
differentiation of hiPSC-derived cardiomyocytes (hiPSC-CMs) induced from diseased …

The heart undergoes a dynamic maturation process following birth, in response to a wide
range of stimuli, including both physiological and pathological cues. This process entails …

Engineered cardiac tissues (ECTs) derived from human induced pluripotent stem cells
(hiPSCs) are viable alternatives for cardiac repair, patient‐specific disease modeling, and …

Cardiovascular diseases remain the leading cause of death worldwide; hence there is an
increasing focus on develo** physiologically relevant in vitro cardiovascular tissue …

Recent innovations in differentiating cardiomyocytes from human induced pluripotent stem
cells (hiPSCs) have unlocked a viable path to creating in vitro cardiac models. Currently …

Heart-on-chip emerged as a potential tool for cardiac tissue engineering, recapitulating key
physiological cues in cardiac pathophysiology. Controlled electrical stimulation and the …

Cardiovascular disease (CVD) remains the leading cause of death worldwide. Natural
compounds extracted from medicinal plants characterized by diverse biological activities …

The mechanical function of the myocardium is defined by cardiomyocyte contractility and the
biomechanics of the extracellular matrix (ECM). Understanding this relationship remains an …

Here an electrical stimulation system is described for maturing microfiber‐shaped cardiac
tissue (cardiac microfibers, CMFs). The system enables stable culturing of CMFs with …

Cardiac contractility modulation (CCM) is a medical device therapy whereby non-excitatory
electrical stimulations are delivered to the myocardium during the absolute refractory period …