Insulin and insulin resistance in Alzheimer's disease

A Sędzikowska, L Szablewski - International journal of molecular sciences, 2021 - mdpi.com
Insulin plays a range of roles as an anabolic hormone in peripheral tissues. It regulates
glucose metabolism, stimulates glucose transport into cells and suppresses hepatic glucose …

Type 2 diabetes mellitus-associated cognitive dysfunction: advances in potential mechanisms and therapies

A Luo, Z **e, Y Wang, X Wang, S Li, J Yan… - Neuroscience & …, 2022 - Elsevier
Abstract Type 2 diabetes (T2D) and its target organ injuries cause distressing impacts on
personal health and put an enormous burden on the healthcare system, and increasing …

Metabolic syndrome, cognitive impairment and the role of diet: a narrative review

M Kouvari, NM D'cunha, N Travica, D Sergi, M Zec… - Nutrients, 2022 - mdpi.com
Background: This narrative review presents the association between metabolic syndrome
(MetS), along with its components, and cognition-related disorders, as well as the potential …

Brain–body communication in metabolic control

A Furlan, P Petrus - Trends in Endocrinology & Metabolism, 2023 - cell.com
A thorough understanding of the mechanisms controlling energy homeostasis is needed to
prevent and treat metabolic morbidities. While the contribution of organs such as the liver …

[HTML][HTML] Biliverdin Reductase-A integrates insulin signaling with mitochondrial metabolism through phosphorylation of GSK3β

C Lanzillotta, A Tramutola, S Lanzillotta, V Greco… - Redox Biology, 2024 - Elsevier
Brain insulin resistance links the failure of energy metabolism with cognitive decline in both
type 2 Diabetes Mellitus (T2D) and Alzheimer's disease (AD), although the molecular …

The gut microbiota is an emerging target for improving brain health during ageing

M Boehme, KE Guzzetta, C Wasén, LM Cox - Gut microbiome, 2023 - cambridge.org
The gut microbiota plays crucial roles in maintaining the health and homeostasis of its host
throughout lifespan, including through its ability to impact brain function and regulate …

Peripheral versus central insulin and leptin resistance: Role in metabolic disorders, cognition, and neuropsychiatric diseases

JM Erichsen, JR Fadel, LP Reagan - Neuropharmacology, 2022 - Elsevier
Insulin and leptin are classically regarded as peptide hormones that play key roles in
metabolism. In actuality, they serve several functions in both the periphery and central …

360-degree perspectives on obesity

M Cuciureanu, CC Caratașu, L Gabrielian… - Medicina, 2023 - mdpi.com
Alarming statistics show that the number of people affected by excessive weight has
surpassed 2 billion, representing approximately 30% of the world's population. The aim of …

Hydrogen sulfide plays an important role by regulating endoplasmic reticulum stress in diabetes-related diseases

H Zhao, H Liu, Y Yang, T Lan, H Wang… - International Journal of …, 2022 - mdpi.com
Endoplasmic reticulum (ER) plays important roles in protein synthesis, protein folding and
modification, lipid biosynthesis, calcium storage, and detoxification. ER homeostasis is …

Retracted Article: The interaction between insulin resistance and Alzheimer's disease: a review article

NY Albar, H Hassaballa, H Shikh, Y Albar… - Postgraduate …, 2024 - Taylor & Francis
Statement of Retraction We, the Editors and Publisher of Postgraduate Medicine, have
retracted the following article: Albar NY, Hassaballa H, Shikh H et al. The interaction …