Carcinomas are complex ecosystems composed of cancer, stromal and immune cells.
Communication between these cells and their microenvironments induces cancer …

Tissues and organs are composed of distinct cell types that must operate in concert to
perform physiological functions. Efforts to create high-dimensional biomarker catalogs of …

With recent advances in the field of single‐atoms (SAs) used in photocatalysis, an
unprecedented performance of atomically dispersed co‐catalysts has been achieved …

The eukaryotic cell is compartmentalized into subcellular niches, including membrane-
bound and membrane-less organelles. Proteins localize to these niches to fulfil their …

Single-cell, spatially resolved omics analysis of tissues is poised to transform biomedical
research and clinical practice. We have developed an open-source, computational histology …

Seipin is a disk-like oligomeric endoplasmic reticulum (ER) protein important for lipid droplet
(LD) biogenesis and triacylglycerol (TAG) delivery to growing LDs. Here we show through …

The efficiency of organic solar cells with donor polymers and non-fullerene acceptors
depends on a complex morphology. Similar chemical and electronic structures impede …

Rationale: Macrophages are essential regulators of atherosclerosis. They secrete cytokines,
process lipoproteins and cholesterol, and take up apoptotic cells. Multiple subsets of plaque …

Obesity is associated with metabolic dysfunction, including insulin resistance and
hyperinsulinemia, and with disorders such as cardiovascular disease, osteoporosis, and …

Polysaccharide breakdown by bacteria requires the activity of enzymes that degrade
polymers either intra-or extra-cellularly. The latter mechanism generates a localized pool of …