Quantifying brain microstructure with diffusion MRI: Theory and parameter estimation
We review, systematize and discuss models of diffusion in neuronal tissue, by putting them
into an overarching physical context of coarse‐graining over an increasing diffusion length …
into an overarching physical context of coarse‐graining over an increasing diffusion length …
On modeling
Map** tissue microstructure with MRI holds great promise as a noninvasive window into
tissue organization at the cellular level. Having originated within the realm of diffusion NMR …
tissue organization at the cellular level. Having originated within the realm of diffusion NMR …
Imaging brain microstructure with diffusion MRI: practicality and applications
This article gives an overview of microstructure imaging of the brain with diffusion MRI and
reviews the state of the art. The microstructure‐imaging paradigm aims to estimate and map …
reviews the state of the art. The microstructure‐imaging paradigm aims to estimate and map …
[HTML][HTML] Connectome 2.0: Develo** the next-generation ultra-high gradient strength human MRI scanner for bridging studies of the micro-, meso-and macro …
The first phase of the Human Connectome Project pioneered advances in MRI technology
for map** the macroscopic structural connections of the living human brain through the …
for map** the macroscopic structural connections of the living human brain through the …
Noninvasive quantification of axon radii using diffusion MRI
Axon caliber plays a crucial role in determining conduction velocity and, consequently, in the
timing and synchronization of neural activation. Noninvasive measurement of axon radii …
timing and synchronization of neural activation. Noninvasive measurement of axon radii …
[HTML][HTML] Challenges for biophysical modeling of microstructure
The biophysical modeling efforts in diffusion MRI have grown considerably over the past 25
years. In this review, we dwell on the various challenges along the journey of bringing a …
years. In this review, we dwell on the various challenges along the journey of bringing a …
Mesoscopic structure of neuronal tracts from time-dependent diffusion
Interpreting brain diffusion MRI measurements in terms of neuronal structure at a micrometer
level is an exciting unresolved problem. Here we consider diffusion transverse to a bundle of …
level is an exciting unresolved problem. Here we consider diffusion transverse to a bundle of …
Microstructural imaging of the human brain with a 'super-scanner': 10 key advantages of ultra-strong gradients for diffusion MRI
The key component of a microstructural diffusion MRI 'super-scanner'is a dedicated high-
strength gradient system that enables stronger diffusion weightings per unit time compared …
strength gradient system that enables stronger diffusion weightings per unit time compared …
[HTML][HTML] Post mortem map** of connectional anatomy for the validation of diffusion MRI
Diffusion MRI (dMRI) is a unique tool for the study of brain circuitry, as it allows us to image
both the macroscopic trajectories and the microstructural properties of axon bundles in vivo …
both the macroscopic trajectories and the microstructural properties of axon bundles in vivo …
In vivo observation and biophysical interpretation of time-dependent diffusion in human white matter
The presence of micrometer-level restrictions leads to a decrease of diffusion coefficient with
diffusion time. Here we investigate this effect in human white matter in vivo. We focus on a …
diffusion time. Here we investigate this effect in human white matter in vivo. We focus on a …