The role of the gut microbiome in colorectal cancer development and therapy response

L Sánchez-Alcoholado, B Ramos-Molina, A Otero… - Cancers, 2020 - mdpi.com
Colorectal cancer (CRC) is the third most common cancer worldwide and the leading cause
of cancer-related deaths. Recently, several studies have demonstrated that gut microbiota …

[HTML][HTML] Dietary long-chain n− 3 fatty acids for the prevention of cancer: a review of potential mechanisms

SC Larsson, M Kumlin, M Ingelman-Sundberg… - The American journal of …, 2004 - Elsevier
Increasing evidence from animal and in vitro studies indicates that n− 3 fatty acids,
especially the long-chain polyunsaturated fatty acids eicosapentaenoic acid and …

The involvement of polyunsaturated fatty acids in apoptosis mechanisms and their implications in cancer

M Montecillo-Aguado, B Tirado-Rodriguez… - International Journal of …, 2023 - mdpi.com
Cancer is a significant global public health issue and, despite advancements in detection
and treatment, the prognosis remains poor. Cancer is a complex disease characterized by …

Inflammaging and cancer: a challenge for the Mediterranean diet

R Ostan, C Lanzarini, E Pini, M Scurti, D Vianello… - nutrients, 2015 - mdpi.com
Aging is considered the major risk factor for cancer, one of the most important mortality
causes in the western world. Inflammaging, a state of chronic, low-level systemic …

Omega-3 polyunsaturated fatty acids for the treatment and prevention of colorectal cancer

AJ Cockbain, GJ Toogood, MA Hull - Gut, 2012 - gut.bmj.com
Omega (ω)-3 polyunsaturated fatty acids (PUFAs) are naturally occurring substances that
are well tolerated and have been used extensively for the prevention of cardiovascular …

Nutrigenomics and nutrigenetics: the emerging faces of nutrition

DM Mutch, W Wahli, G Williamson - The FASEB journal, 2005 - Wiley Online Library
The recognition that nutrients have the ability to interact and modulate molecular
mechanisms underlying an organism's physiological functions has prompted a revolution in …

[HTML][HTML] Microbial degradation products influence colon cancer risk: the butyrate controversy

JR Lupton - The Journal of nutrition, 2004 - Elsevier
All dietary fiber, by definition, escapes digestion in the small intestine and thus arrives
relatively intact in the large intestine. Its fate in the large intestine depends upon the type of …

Pectin induces apoptosis in human prostate cancer cells: correlation of apoptotic function with pectin structure

CL Jackson, TM Dreaden, LK Theobald, NM Tran… - …, 2007 - academic.oup.com
Abstract Treatment options for androgen-independent prostate cancer cells are limited.
Therefore, it is critical to identify agents that induce death of both androgen-responsive and …

Membrane lipid raft organization is uniquely modified by n-3 polyunsaturated fatty acids

HF Turk, RS Chapkin - Prostaglandins, Leukotrienes and Essential Fatty …, 2013 - Elsevier
Fish oil, enriched in bioactive n-3 polyunsaturated fatty acids (PUFA), has been shown to
play a role in prevention of colon cancer. The effects of n-3 PUFA are pleiotropic and …

Therapeutic potential of n-3 polyunsaturated fatty acids in disease

JW Fetterman Jr, MM Zdanowicz - American journal of health …, 2009 - academic.oup.com
Purpose. The potential therapeutic benefits of supplementation with n-3 polyunsaturated
fatty acids (PUFAs) in various diseases are reviewed, and the antiinflammatory actions …