Adaptive laboratory evolution principles and applications in industrial biotechnology
Adaptive laboratory evolution (ALE) is an innovative approach for the generation of evolved
microbial strains with desired characteristics, by implementing the rules of natural selection …
microbial strains with desired characteristics, by implementing the rules of natural selection …
The evolutionary significance of polyploidy
Polyploidy, or the duplication of entire genomes, has been observed in prokaryotic and
eukaryotic organisms, and in somatic and germ cells. The consequences of polyploidization …
eukaryotic organisms, and in somatic and germ cells. The consequences of polyploidization …
Genetics of adaptation
The rediscovery of Mendel's work showing that the heredity of phenotypes is controlled by
discrete genes was followed by the reconciliation of Mendelian genetics with evolution by …
discrete genes was followed by the reconciliation of Mendelian genetics with evolution by …
Domestication and divergence of Saccharomyces cerevisiae beer yeasts
Whereas domestication of livestock, pets, and crops is well documented, it is still unclear to
what extent microbes associated with the production of food have also undergone human …
what extent microbes associated with the production of food have also undergone human …
Physiology, ecology and industrial applications of aroma formation in yeast
Yeast cells are often employed in industrial fermentation processes for their ability to
efficiently convert relatively high concentrations of sugars into ethanol and carbon dioxide …
efficiently convert relatively high concentrations of sugars into ethanol and carbon dioxide …
Revisiting adaptive potential, population size, and conservation
Additive genetic variance (VA) reflects the potential for evolutionary shifts and can be low for
some traits or populations. High VA is critical for the conservation of threatened species …
some traits or populations. High VA is critical for the conservation of threatened species …
[HTML][HTML] The consequences of chromosome segregation errors in mitosis and meiosis
Mistakes during cell division frequently generate changes in chromosome content,
producing aneuploid or polyploid progeny cells. Polyploid cells may then undergo abnormal …
producing aneuploid or polyploid progeny cells. Polyploid cells may then undergo abnormal …
[HTML][HTML] Origins, evolution, domestication and diversity of Saccharomyces beer yeasts
Highlights•Traditional beer brewing provided the perfect setting for microbial domestication.•
Saccharomyces beer yeasts have been domesticated on multiple occasions.•Domestication …
Saccharomyces beer yeasts have been domesticated on multiple occasions.•Domestication …
[HTML][HTML] Under pressure: evolutionary engineering of yeast strains for improved performance in fuels and chemicals production
Highlights•Recent technological advances amplify the power of yeast evolutionary
engineering.•Dynamic selection regimes can mitigate phenotypic trade-off …
engineering.•Dynamic selection regimes can mitigate phenotypic trade-off …
Identifying and characterizing SCRaMbLEd synthetic yeast using ReSCuES
SCRaMbLE is a novel system implemented in the synthetic yeast genome, enabling
massive chromosome rearrangements to produce strains with a large genotypic diversity …
massive chromosome rearrangements to produce strains with a large genotypic diversity …