Pulmonary vascular remodeling is the key structural alteration in pulmonary hypertension
and involves changes in the intima, media and adventitia, often with the interplay of …

Pulmonary arterial hypertension (PAH) is a disease characterized by progressive
remodeling of the distal pulmonary arteries, resulting in the loss of vascular cross-sectional …

Background: We hypothesized that pulmonary venous hypertension in heart failure (HF)
leads to predominate remodeling of pulmonary veins and that the severity of venous …

Pregnancy outcomes in patients with pulmonary hypertension remain poor despite
advanced therapies. Although consensus guidelines recommend against pregnancy in …

Pulmonary hypertension (PH) encompasses a syndrome of diseases that are characterized
by elevated pulmonary artery pressure and pulmonary vascular remodeling and that …

Hypoxic pulmonary hypertension (PH) comprises a heterogeneous group of diseases
sharing the common feature of chronic hypoxia-induced pulmonary vascular remodeling …

Rationale: Pulmonary arterial hypertension (PAH) is a devastating disease characterized by
progressive vasoconstriction and obliterative vascular remodeling that leads to right heart …

It is well established that control of vascular morphogenesis and homeostasis is regulated
by vascular endothelial growth factor (VEGF), fibroblast growth factor (FGF), Delta-like 4 …

KCEK and KRS conceived the study, delineated the hypotheses, designed the study,
analyzed and interpreted data, and prepared the manuscript; SRR, HKE, ALA, MGF, ML …

Rationale: Angioproliferative vasculopathy is a hallmark of pulmonary arterial hypertension
(PAH). However, little is known about how endothelial cell (EC) and smooth muscle cell …