Primary sclerosing cholangitis (PSC) is a rare disorder characterised by multi-focal bile duct
strictures and progressive liver disease. Inflammatory bowel disease is usually present and …

Primary sclerosing cholangitis is a rare, chronic cholestatic liver disease characterised by
intrahepatic or extrahepatic stricturing, or both, with bile duct fibrosis. Inflammation and …

Management of primary or secondary sclerosing cholangitis is challenging. These Clinical
Practice Guidelines have been developed to provide practical guidance on debated topics …

Primary bile acids serve important roles in cholesterol metabolism, lipid digestion, host-
microbe interactions, and regulatory pathways in the human host. While most bile acids are …

These guidelines on the management of primary sclerosing cholangitis (PSC) were
commissioned by the British Society of Gastroenterology liver section. The guideline writing …

Primary sclerosing cholangitis (PSC) represents a major unmet medical need. In a phase II
double‐blind, placebo‐controlled study, we tested the safety and efficacy of cilofexor …

Primary sclerosing cholangitis is the classic hepatobiliary manifestation of inflammatory
bowel disease and is generally chronic and progressive. Patients frequently present with …

Background & Aim Primary sclerosing cholangitis (PSC) represents a devastating bile duct
disease, currently lacking effective medical therapy. 24-norursodeoxycholic acid (norUDCA) …

EASL Clinical Practice Guidelines (CPG) on the management of cholestatic liver diseases
define the use of diagnostic, therapeutic and preventive modalities, including non-invasive …

This guideline has been approved by the American Association for the Study of Liver
Diseases and represents the position of the Association. These recommendations provide a …