Remodeling in asthma

S Al-Muhsen, JR Johnson, Q Hamid - Journal of allergy and clinical …, 2011 - Elsevier
Airway remodeling encompasses the structural alterations in asthmatic compared with
normal airways. Airway remodeling in asthmatic patients involves a wide array of …

Tenascins: regulation and putative functions during pathological stress

R Chiquet‐Ehrismann, M Chiquet - The Journal of Pathology: A …, 2003 - Wiley Online Library
In this review, we discuss the structure and function of the extracellular matrix protein family
of tenascins with emphasis on their involvement in human pathologies. The article is divided …

The role of tenascin-C in tissue injury and tumorigenesis

KS Midwood, G Orend - Journal of cell communication and signaling, 2009 - Springer
The extracellular matrix molecule tenascin-C is highly expressed during embryonic
development, tissue repair and in pathological situations such as chronic inflammation and …

Interrelated role of cigarette smoking, oxidative stress, and immune response in COPD and corresponding treatments

L Zuo, F He, GG Sergakis… - … of Physiology-Lung …, 2014 - journals.physiology.org
Cigarette smoking (CS) can impact the immune system and induce pulmonary disorders
such as chronic obstructive pulmonary disease (COPD), which is currently the fourth leading …

Impact of smoking on inflammation: overview of molecular mechanisms

RB Gonçalves, RD Coletta, KG Silvério… - Inflammation …, 2011 - Springer
Background Inflammation is a critical component of normal tissue repair, as well as being
fundamental to the body's defense against infection. Environmental factors, such as …

Human pathogens utilize host extracellular matrix proteins laminin and collagen for adhesion and invasion of the host

B Singh, C Fleury, F Jalalvand… - FEMS microbiology …, 2012 - academic.oup.com
Laminin (Ln) and collagen are multifunctional glycoproteins that play an important role in
cellular morphogenesis, cell signalling, tissue repair and cell migration. These proteins are …

A review of pulmonary toxicity of electronic cigarettes in the context of smoking: a focus on inflammation

PG Shields, M Berman, TM Brasky… - … Biomarkers & Prevention, 2017 - AACR
The use of electronic cigarettes (e-cigs) is increasing rapidly, but their effects on lung toxicity
are largely unknown. Smoking is a well-established cause of lung cancer and respiratory …

Phenotypes, risk factors, and mechanisms of adult‐onset asthma

P Ilmarinen, LE Tuomisto… - Mediators of …, 2015 - Wiley Online Library
Asthma is a heterogeneous disease with many phenotypes, and age at disease onset is an
important factor in separating the phenotypes. Genetic factors, atopy, and early respiratory …

[PDF][PDF] Effects of cigarette smoke on the lung and systemic immunity

J Domagala-Kulawik - J Physiol Pharmacol, 2008 - jpp.krakow.pl
The influence of tobacco smoke on human health is still an important problem worldwide.
Complex inflammatory processes and changes in the immune system are crucial in the …

Impact of pollen

LA De Weger, KC Bergmann… - Allergenic pollen: A …, 2013 - Springer
The impact of pollen on human health is primarily evident in allergic diseases. Sensitized
patients can respond to pollen by symptoms of nose, eyes and bronchi. Pollen threshold …