Osteoarthritis (OA) remains the most challenging arthritic disorder, with a high burden of
disease and no available disease-modifying treatments. Symptomatic early-stage OA of the …

Being the most common musculoskeletal progressive condition, osteoarthritis is an
interesting target for research. It is estimated that the prevalence of knee osteoarthritis (OA) …

Osteoarthritis (OA) is a chronic joint disease caused by disruption of joint homeostasis by a
variety of systemic and biomechanical factors. The disease is characterized by degradation …

Osteoarthritis (OA) has traditionally been defined as a prototypical non-inflammatory
arthropathy, but today there is compelling evidence to suggest that it has an inflammatory …

The menisci are internal structures that are of central importance for a healthy knee joint;
they have a key role in the structural progression of knee osteoarthritis (OA), and the risk of …

Globally, osteoarthritis (OA) is the most prevalent arthritic condition in those aged over 60
years. OA has a high impact on patient disability and is associated with a significant …

Knee osteoarthritis (OA) is one of the most prevalent forms of this disease, with the medial
compartment most commonly affected. The direction of external forces and limb orientation …

The role of the quadriceps muscle in mediating risk for knee osteoarthritis (OA) is a common
subject of investigation. The quadriceps muscle is a principal contributor to knee joint …

There is no disease-modifying therapy for osteoarthritis, a degenerative joint disease that is
projected to afflict more than 67 million individuals in the United States alone by 2030 …

In this review, we have focused on the molecular biomarkers of four distinct osteoarthritis
subtypes including inflammatory, subchondral bone remodelling, metabolic syndrome and …