Tumor immune microenvironment lncRNAs

EG Park, SJ Pyo, Y Cui, SH Yoon… - Briefings in …, 2022 - academic.oup.com
Long non-coding ribonucleic acids (RNAs)(lncRNAs) are key players in tumorigenesis and
immune responses. The nature of their cell type-specific gene expression and other …

Liquid biopsy in gastric cancer: predictive and prognostic biomarkers

Z Zhang, H Wu, W Chong, L Shang, C **g, L Li - Cell death & disease, 2022 - nature.com
Gastric cancer (GC) is a high-incidence cancer worldwide. Most patients are diagnosed at
an advanced stage, by which time they have limited treatment options and poor prognosis …

[HTML][HTML] Machine learning-based identification of tumor-infiltrating immune cell-associated lncRNAs for improving outcomes and immunotherapy responses in patients …

N Zhang, H Zhang, W Wu, R Zhou, S Li, Z Wang… - Theranostics, 2022 - ncbi.nlm.nih.gov
Rationale: Accumulating evidence demonstrated that long noncoding RNAs (lncRNAs)
involved in the regulation of the immune system and displayed a cell-type-specific pattern in …

Machine learning-based tumor-infiltrating immune cell-associated lncRNAs for predicting prognosis and immunotherapy response in patients with glioblastoma

H Zhang, N Zhang, W Wu, R Zhou, S Li… - Briefings in …, 2022 - academic.oup.com
Long noncoding ribonucleic acids (RNAs; lncRNAs) have been associated with cancer
immunity regulation. However, the roles of immune cell-specific lncRNAs in glioblastoma …

RNA m6A demethylase FTO-mediated epigenetic up-regulation of LINC00022 promotes tumorigenesis in esophageal squamous cell carcinoma

Y Cui, C Zhang, S Ma, Z Li, W Wang, Y Li, Y Ma… - Journal of Experimental …, 2021 - Springer
Background Long non-coding RNA (LncRNA) controls cell proliferation and plays a
significant role in the initiation and progression of esophageal squamous cell carcinoma …

Molecular characterization, biological function, tumor microenvironment association and clinical significance of m6A regulators in lung adenocarcinoma

Y Li, J Gu, F Xu, Q Zhu, Y Chen, D Ge… - Briefings in …, 2021 - academic.oup.com
Abstract N6-methyladenosine (m6A) modification can regulate a variety of biological
processes. However, the implications of m6A modification in lung adenocarcinoma (LUAD) …

Computational recognition of lncRNA signature of tumor-infiltrating B lymphocytes with potential implications in prognosis and immunotherapy of bladder cancer

M Zhou, Z Zhang, S Bao, P Hou, C Yan… - Briefings in …, 2021 - academic.oup.com
Long noncoding RNAs (lncRNAs) have been associated with cancer immunity regulation
and the tumor microenvironment (TME). However, functions of lncRNAs of tumor-infiltrating …

m6A regulator‐mediated RNA methylation modification patterns are involved in immune microenvironment regulation of periodontitis

X Zhang, S Zhang, X Yan, Y Shan, L Liu… - Journal of cellular …, 2021 - Wiley Online Library
The role of epigenetic regulation in immunity is emerging, especially for RNA N6‐
methyladenosine (m6A) modification. However, little is known about the role of m6A in the …

From carcinogenesis to therapeutic avenues: lncRNAs and mTOR crosstalk in lung cancer

MS Hussain, ASA Altamimi, M Afzal, I Kazmi… - … -Research and Practice, 2024 - Elsevier
Long non-coding RNAs (lncRNAs) have been demonstrated to have a crucial function in the
modulation of the activity of genes, impacting a variety of homeostatic processes involving …

Non‐coding RNAs in cancer immunotherapy: Predictive biomarkers and targets

M Alahdal, E Elkord - Clinical and translational medicine, 2023 - Wiley Online Library
Background To date, standardising clinical predictive biomarkers for assessing the response
to immunotherapy remains challenging due to variations in personal genetic signatures …