The completion of the Human Genome Project has provided a foundational blueprint for
understanding human life. Nonetheless, understanding the intricate mechanisms through …

In the analysis of spatially resolved transcriptomics data, detecting spatially variable genes
(SVGs) is crucial. Numerous computational methods exist, but varying SVG definitions and …

Identifying spatially variable genes (SVGs) is critical in linking molecular cell functions with
tissue phenotypes. Spatially resolved transcriptomics captures cellular-level gene …

Spatially resolved transcriptomics involves a set of emerging technologies that enable the
transcriptomic profiling of tissues with the physical location of expressions. Although a …

Spatially resolved transcriptomics technologies provide high-throughput measurements of
gene expression in a tissue slice, but the sparsity of these data complicates analysis of …

Integrated single cell and unsupervised spatial transcriptomic analysis defines molecular
anatomy of the human dorsolateral prefrontal cortex - PMC Back to Top Skip to main content NIH …

The molecular organization of the human neocortex historically has been studied in the
context of its histological layers. However, emerging spatial transcriptomic technologies …

Background The identification of genes that vary across spatial domains in tissues and cells
is an essential step for spatial transcriptomics data analysis. Given the critical role it serves …

Identifying spatially variable genes (SVGs) is a key step in the analysis of spatially resolved
transcriptomics data. SVGs provide biological insights by defining transcriptomic differences …

Spatial transcriptomics (ST) represents a revolutionary approach in molecular biology,
providing unprecedented insights into the spatial organization of gene expression within …