Some viral outbreaks have plagued the world since antiquity, including the most recent
COVID-19 pandemic. The continuous spread and emergence of new viral diseases have …

Azepane-based compounds showed a variety of pharmacological properties, and its
derivatives possess a high degree of structural diversity, and it is useful for the discovery of …

Many membrane-resident and secrected proteins, including growth factors and their
receptors, are N-glycosylated. The initial N-glycan structure is synthesized in the …

Three decades after their first synthesis, iminosugar C-glycosides have become an
important class of iminosugars with promising biological and therapeutic properties. The …

A bunch of keys, one lock: The multivalent effect in glycosidase inhibition is a new, rapidly
emerging area with exciting potential and scope. This review presents a description of the …

Glycosidases are ubiquitous enzymes involved in a diversity of key biological processes
such as energy uptake or cell wall degradation. The design of specific glycosidase inhibitors …

α-Glucosidase inhibitors are marketed as therapeutic drugs for diabetes that act through the
inhibition of carbohydrate metabolism. Inhibitors of the α-glucosidases that are involved in …

Covering: 2005 to the end of 2009 In addition to their clinical importance in the treatment of
type II diabetes, α-glucosidase inhibitors have attracted considerable attention from the …

Inhibition of carbohydrate processing enzymes is a topic of great interest, as these enzymes
are involved in a plethora of key biochemical events, such as digestion, lysosomal …

Newly emerged xanthone derivatives have attracted considerable interests as a novel class
of potent α-glucosidase inhibitors. To provide insights into the inhibitory and binding …