Solid-state NMR: Methods for biological solids

S Ahlawat, KR Mote, NA Lakomek… - Chemical Reviews, 2022 - ACS Publications
In the last two decades, solid-state nuclear magnetic resonance (ssNMR) spectroscopy has
transformed from a spectroscopic technique investigating small molecules and industrial …

Solid-state NMR spectroscopy

B Reif, SE Ashbrook, L Emsley, M Hong - Nature Reviews Methods …, 2021 - nature.com
Solid-state nuclear magnetic resonance (NMR) spectroscopy is an atomic-level method to
determine the chemical structure, 3D structure and dynamics of solids and semi-solids. This …

Structure and drug binding of the SARS-CoV-2 envelope protein transmembrane domain in lipid bilayers

VS Mandala, MJ McKay, AA Shcherbakov… - Nature structural & …, 2020 - nature.com
An essential protein of the SARS-CoV-2 virus, the envelope protein E, forms a
homopentameric cation channel that is important for virus pathogenicity. Here we report a …

The ladder of life detection

M Neveu, LE Hays, MA Voytek, MH New, MD Schulte - Astrobiology, 2018 - liebertpub.com
We describe the history and features of the Ladder of Life Detection, a tool intended to guide
the design of investigations to detect microbial life within the practical constraints of robotic …

Rapid proton-detected NMR assignment for proteins with fast magic angle spinning

E Barbet-Massin, AJ Pell, JS Retel… - Journal of the …, 2014 - ACS Publications
Using a set of six 1H-detected triple-resonance NMR experiments, we establish a method for
sequence-specific backbone resonance assignment of magic angle spinning (MAS) nuclear …

Solid‐state NMR spectroscopic methods in chemistry

DD Laws, HML Bitter, A Jerschow - Angewandte Chemie …, 2002 - Wiley Online Library
Over the last decades, NMR spectroscopy has grown into an indispensable tool for chemical
analysis, structure determination, and the study of dynamics in organic, inorganic, and …

3D TEDOR NMR Experiments for the Simultaneous Measurement of Multiple Carbon−Nitrogen Distances in Uniformly 13C,15N-Labeled Solids

CP Jaroniec, C Filip, RG Griffin - Journal of the American …, 2002 - ACS Publications
We describe three-dimensional magic-angle-spinning NMR experiments for the
simultaneous measurement of multiple carbon− nitrogen distances in uniformly 13C, 15N …

Dynamic nuclear polarization with a rigid biradical

Y Matsuki, T Maly, O Ouari, H Karoui… - Angewandte Chemie …, 2009 - Wiley Online Library
A new polarizing agent with superior performance in dynamic nuclear polarization
experiments is introduced, and utilizes two TEMPO (2, 2, 6, 6‐tetramethylpiperidine‐1‐oxyl) …

Dynamic nuclear polarization at 9 T using a novel 250 GHz gyrotron microwave source

VS Bajaj, CT Farrar, MK Hornstein, I Mastovsky… - Journal of Magnetic …, 2011 - Elsevier
In this communication, we report enhancements of nuclear spin polarization by dynamic
nuclear polarization (DNP) in static and spinning solids at a magnetic field strength of 9T …

Broadband homonuclear correlation spectroscopy driven by combined R2nv sequences under fast magic angle spinning for NMR structural analysis of organic and …

G Hou, S Yan, J Trebosc, JP Amoureux… - Journal of Magnetic …, 2013 - Elsevier
We recently described a family of experiments for R2nv Driven Spin Diffusion (RDSD)
spectroscopy suitable for homonuclear correlation experiments under fast MAS conditions …