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[HTML][HTML] The global burden of liver disease
Chronic liver disease (CLD) and its associated complications (cirrhosis and liver cancer)
cause significant mortality, morbidity, and economic burden. Published data from the World …
cause significant mortality, morbidity, and economic burden. Published data from the World …
[HTML][HTML] Global prevalence and genotype distribution of hepatitis C virus infection in 2015: a modelling study
Summary Background The 69th World Health Assembly approved the Global Health Sector
Strategy to eliminate hepatitis C virus (HCV) infection by 2030, which can become a reality …
Strategy to eliminate hepatitis C virus (HCV) infection by 2030, which can become a reality …
Approved antiviral drugs over the past 50 years
Since the first antiviral drug, idoxuridine, was approved in 1963, 90 antiviral drugs
categorized into 13 functional groups have been formally approved for the treatment of the …
categorized into 13 functional groups have been formally approved for the treatment of the …
Oral direct-acting agent therapy for hepatitis C virus infection: a systematic review
Background: Rapid improvements in hepatitis C virus (HCV) therapy have led to the
approval of multiple oral direct-acting antiviral (DAA) regimens by the US Food and Drug …
approval of multiple oral direct-acting antiviral (DAA) regimens by the US Food and Drug …
Global epidemiology of hepatitis C virus infection: An up-date of the distribution and circulation of hepatitis C virus genotypes
AIM To review Hepatitis C virus (HCV) prevalence and genotypes distribution worldwide.
METHODS We conducted a systematic study which represents one of the most …
METHODS We conducted a systematic study which represents one of the most …
EASL recommendations on treatment of hepatitis C 2016
European Association for The Study of The Liver - Journal of hepatology, 2017 - Elsevier
Hepatitis C virus (HCV) infection is one of the main causes of chronic liver disease
worldwide [1]. The long-term impact of HCV infection is highly variable, ranging from minimal …
worldwide [1]. The long-term impact of HCV infection is highly variable, ranging from minimal …
Sofosbuvir and velpatasvir for HCV genotype 1, 2, 4, 5, and 6 infection
Background A simple treatment regimen that is effective in a broad range of patients who are
chronically infected with the hepatitis C virus (HCV) remains an unmet medical need …
chronically infected with the hepatitis C virus (HCV) remains an unmet medical need …
Identification of a novel hepatitis C virus genotype from Punjab, India: expanding classification of hepatitis C virus into 8 genotypes
SM Borgia, C Hedskog, B Parhy… - The Journal of …, 2018 - academic.oup.com
Abstract Background Hepatitis C virus (HCV) exhibits great genetic diversity and is classified
into 7 genotypes (GTs), with varied geographic prevalence. Until the recent development of …
into 7 genotypes (GTs), with varied geographic prevalence. Until the recent development of …
Glecaprevir plus pibrentasvir for chronic hepatitis C virus genotype 1, 2, 4, 5, or 6 infection in adults with compensated cirrhosis (EXPEDITION-1): a single-arm, open …
X Forns, SS Lee, J Valdes, S Lens, R Ghalib… - The Lancet infectious …, 2017 - thelancet.com
Background The once-daily, ribavirin-free, pangenotypic, direct-acting antiviral regimen,
glecaprevir coformulated with pibrentasvir, has shown high rates of sustained virological …
glecaprevir coformulated with pibrentasvir, has shown high rates of sustained virological …
Global epidemiology and burden of HCV infection and HCV-related disease
Chronic HCV infection is a global health problem that affects> 184 million people worldwide.
HCV is associated with several hepatic and extrahepatic disorders, including several …
HCV is associated with several hepatic and extrahepatic disorders, including several …