Navigating the collagen jungle: the biomedical potential of fiber organization in cancer
Recent research has highlighted the importance of key tumor microenvironment features,
notably the collagen-rich extracellular matrix (ECM) in characterizing tumor invasion and …
notably the collagen-rich extracellular matrix (ECM) in characterizing tumor invasion and …
The extracellular matrix in epithelial ovarian cancer–a piece of a puzzle
A Cho, VM Howell, EK Colvin - Frontiers in oncology, 2015 - frontiersin.org
Epithelial ovarian cancer is the fifth leading cause of cancer-related deaths in women and
the most lethal gynecological malignancy. Extracellular matrix (ECM) is an integral …
the most lethal gynecological malignancy. Extracellular matrix (ECM) is an integral …
[HTML][HTML] Large-scale tumor-associated collagen signatures identify high-risk breast cancer patients
G **, W Guo, D Kang, J Ma, F Fu, L Qiu, L Zheng… - Theranostics, 2021 - ncbi.nlm.nih.gov
The notion of personalized medicine demands proper prognostic biomarkers to guide the
optimal therapy for an invasive breast cancer patient. However, various risk prediction …
optimal therapy for an invasive breast cancer patient. However, various risk prediction …
[HTML][HTML] Increased expression of several collagen genes is associated with drug resistance in ovarian cancer cell lines
R Januchowski, M Świerczewska, K Sterzyńska… - Journal of …, 2016 - ncbi.nlm.nih.gov
Ovarian cancer is the most lethal gynaecological cancer. The main reason for the high
mortality among ovarian cancer patients is the development of drug resistance. The …
mortality among ovarian cancer patients is the development of drug resistance. The …
Deep learning autofluorescence-harmonic microscopy
Laser scanning microscopy has inherent tradeoffs between imaging speed, field of view
(FOV), and spatial resolution due to the limitations of sophisticated mechanical and optical …
(FOV), and spatial resolution due to the limitations of sophisticated mechanical and optical …
An engineered breast cancer model on a chip to replicate ECM‐activation in vitro during tumor progression
In this work, a new model of breast cancer is proposed featuring both epithelial and stromal
tissues arranged on a microfluidic chip. The main task of the work is the in vitro replication of …
tissues arranged on a microfluidic chip. The main task of the work is the in vitro replication of …
Research of pulmonary fibrosis lesions based on FLIM and SHG imaging microscopy
W Li, X Li, C Zhang, H Wang, Y Zhu, Y Wang… - Analytical …, 2024 - ACS Publications
Two-photon fluorescence lifetime microscopy (TP-FLIM) is a powerful quantitative imaging
technique that characterizes and analyzes the structure and function of biological samples …
technique that characterizes and analyzes the structure and function of biological samples …
Applications of second-harmonic generation imaging microscopy in ovarian and breast cancer
In this perspective, we discuss how the nonlinear optical technique of second-harmonic
generation (SHG) microscopy has been used to greatly enhance our understanding of the …
generation (SHG) microscopy has been used to greatly enhance our understanding of the …
3D texture analysis for classification of second harmonic generation images of human ovarian cancer
Remodeling of the collagen architecture in the extracellular matrix (ECM) has been
implicated in ovarian cancer. To quantify these alterations we implemented a form of 3D …
implicated in ovarian cancer. To quantify these alterations we implemented a form of 3D …
Influence of hematoxylin and eosin staining on the quantitative analysis of second harmonic generation imaging of fixed tissue sections
Second harmonic generation (SHG) microscopy has emerged over the past two decades as
a powerful tool for tissue characterization and diagnostics. Its main applications in medicine …
a powerful tool for tissue characterization and diagnostics. Its main applications in medicine …