Cholestasis is the predominate feature of many pediatric hepatobiliary diseases. The
physiologic flow of bile requires multiple complex processes working in concert. Bile acid …

Biliary atresia (BA) is a common cause of surgical jaundice during the neonatal period. It is
currently considered as a spectrum of diseases with a common final pathology characterized …

Objective To provide a comprehensive, evidence-based overview of the risk factors,
prevention, diagnosis, imaging, treatment and prognosis for Achilles tendinopathy. To make …

Abstract Background and Aims The European Liver Transplant Registry (ELTR) has
collected data on liver transplant procedures performed in Europe since 1968. Approach …

Liver transplantation currently represents a therapeutic option for patients with Wilson
disease presenting with end-stage liver disease or acute liver failure. Indeed, it has been …

Homozygous familial hypercholesterolaemia is a life-threatening genetic condition, which
causes extremely elevated LDL-C levels and atherosclerotic cardiovascular disease very …

Background & Aims Mortality on the paediatric liver transplantation (pLT) waiting list (WL) is
still an issue. We analysed the Italian pLT WL to evaluate the intention-to-treat (ITT) success …

Liver transplant (LT) has become the standard of care for pediatric patients with end-stage
liver disease. In fact, the first attempted liver transplant in a human was performed on a 3 …

Objective: Learning health systems (LHS) integrate research, improvement, management,
and patient care, such that every child receives “the right care at the right time... every time,” …

Background The present study aimed at investigating long‐term mortality of patients who
underwent solid organ transplantation during childhood and at identifying their causes of …