Tissue imaging has become much more colourful in the past decade. Advances in both
experimental and analytical methods now make it possible to image protein markers in …

Although virus–host interactions are usually studied in a single cell type using in vitro assays
in immortalized cell lines or isolated cell populations, it is important to remember that what is …

Single-cell technologies have recently allowed the identification of multiple lymphatic
endothelial cell (LEC) subsets in subcapsular, paracortical, medullary, and other lymph …

The spatial anatomy of hematopoiesis in the bone marrow (BM) has been extensively
studied in mice and other preclinical models, but technical challenges have precluded a …

Follicular lymphoma (FL) is a generally incurable malignancy that originates from
developmentally blocked germinal center B cells residing, primarily, within lymph nodes …

Enhancing our understanding of lymphatic anatomy from the microscopic to the anatomical
scale is essential to discern how the structure and function of the lymphatic system interacts …

Follicular lymphoma (FL) is the most common indolent lymphoma originating from germinal
center B cells. FL represents a clinically and biologically heterogeneous disease. Most …

An early event in the genesis of follicular lymphoma (FL) is the acquisition of new
glycosylation motifs in the B-cell receptor (BCR) due to gene rearrangement and/or somatic …

Lymphomas are a heterogenous group of lymphoid neoplasms with a wide variety of clinical
presentations. Response to treatment and prognosis differs both between and within …

Multiplex ion beam imaging (MIBI) and imaging mass cytometry (IMC) enable highly
multiplexed antibody (40+) staining of frozen or formalin fixed, paraffin-embedded (FFPE) …