Petroselinum crispum L., essential oil as promising source of bioactive compounds, antioxidant, antimicrobial activities: In vitro and in silico predictions

G Nouioura, N El Hachlafi, HA Abuelizz, AE Elidrissi… - Heliyon, 2024 - cell.com
This exploratory study aims to identify the volatile compounds in PC-Eo (Petroselinum
crispum L. essential oil) and evaluate its antioxidant and antimicrobial properties in vitro …

Synthesis, Characterization, DFT mechanistic study, Antibacterial Activity, Molecular modeling, and ADMET properties of novel chromone-isoxazole hybrids

R Bouzammit, S Belchkar, M El Fadili… - Journal of Molecular …, 2024 - Elsevier
A series of novel hybrid heterocycles incorporating isoxazole rings have been successfully
synthesized, characterized, and evaluated for their antibacterial responses. The synthesized …

Design of novel potent selective survivin inhibitors using 2D-QSAR modeling, molecular docking, molecular dynamics, and ADMET properties of new MX-106 …

M Aloui, S Mujwar, S Er-rahmani, HA Abuelizz… - Heliyon, 2024 - cell.com
Given the critical role of survivin (BIRC5) in tumor cell regulation, develo** novel inhibitors
represents a promising approach for cancer therapy. This study details the design of …

Ferula communis leaf extract: antioxidant capacity, UHPLC–MS/MS analysis, and in vivo and in silico toxicity investigations

I Ed-Dahmani, M El Fadili, G Nouioura, F Kandsi… - Frontiers in …, 2025 - frontiersin.org
Introduction Ferula communis has demonstrated an abundance of pharmacological and
antioxidative qualities. Methods This study investigates the antioxidant activity of F …

New Triazole-Isoxazole Hybrids as Antibacterial Agents: Design, Synthesis, Characterization, In Vitro, and In Silico Studies

R Bouzammit, S Belchkar, M El Fadili, Y Kanzouai… - Molecules, 2024 - mdpi.com
Novel isoxazole–triazole conjugates have been efficiently synthesized using 3-
formylchromone as starting material according to a multi-step synthetic approach. The …