Function and therapeutic value of astrocytes in neurological diseases
Astrocytes are abundant glial cells in the central nervous system (CNS) that perform diverse
functions in health and disease. Astrocyte dysfunction is found in numerous diseases …
functions in health and disease. Astrocyte dysfunction is found in numerous diseases …
Multiple sclerosis: Neuroimmune crosstalk and therapeutic targeting
M Charabati, MA Wheeler, HL Weiner, FJ Quintana - Cell, 2023 - cell.com
Multiple sclerosis (MS) is a chronic inflammatory and degenerative disease of the central
nervous system afflicting nearly three million individuals worldwide. Neuroimmune …
nervous system afflicting nearly three million individuals worldwide. Neuroimmune …
Neuroinflammation in neurodegenerative disorders: the roles of microglia and astrocytes
HS Kwon, SH Koh - Translational neurodegeneration, 2020 - Springer
Neuroinflammation is associated with neurodegenerative diseases, such as Alzheimer's
disease, Parkinson's disease, and amyotrophic lateral sclerosis. Microglia and astrocytes …
disease, Parkinson's disease, and amyotrophic lateral sclerosis. Microglia and astrocytes …
Astrocyte crosstalk in CNS inflammation
M Linnerbauer, MA Wheeler, FJ Quintana - Neuron, 2020 - cell.com
Astrocytes control multiple processes in the nervous system in health and disease. It is now
clear that specific astrocyte subsets or activation states are associated with specific genomic …
clear that specific astrocyte subsets or activation states are associated with specific genomic …
Astrocytes in human central nervous system diseases: a frontier for new therapies
A Verkhratsky, A Butt, B Li, P Illes, R Zorec… - … and Targeted Therapy, 2023 - nature.com
Astroglia are a broad class of neural parenchymal cells primarily dedicated to homoeostasis
and defence of the central nervous system (CNS). Astroglia contribute to the …
and defence of the central nervous system (CNS). Astroglia contribute to the …
Microglia and central nervous system–associated macrophages—from origin to disease modulation
The immune system of the central nervous system (CNS) consists primarily of innate
immune cells. These are highly specialized macrophages found either in the parenchyma …
immune cells. These are highly specialized macrophages found either in the parenchyma …
Neuroinflammatory markers: key indicators in the pathology of neurodegenerative diseases
Neuroinflammation, a protective response of the central nervous system (CNS), is
associated with the pathogenesis of neurodegenerative diseases. The CNS is composed of …
associated with the pathogenesis of neurodegenerative diseases. The CNS is composed of …
The role of astrocytes in CNS inflammation
F Giovannoni, FJ Quintana - Trends in immunology, 2020 - cell.com
Astrocytes are the most abundant cell type in the central nervous system (CNS), performing
complex functions in health and disease. It is now clear that multiple astrocyte subsets or …
complex functions in health and disease. It is now clear that multiple astrocyte subsets or …
Gut-licensed IFNγ+ NK cells drive LAMP1+TRAIL+ anti-inflammatory astrocytes
Astrocytes are glial cells that are abundant in the central nervous system (CNS) and that
have important homeostatic and disease-promoting functions. However, little is known about …
have important homeostatic and disease-promoting functions. However, little is known about …
Barcoded viral tracing of single-cell interactions in central nervous system inflammation
INTRODUCTION Glial cells of the central nervous system (CNS), including astrocytes and
microglia, play critical roles in development, tissue repair, and homeostasis. However …
microglia, play critical roles in development, tissue repair, and homeostasis. However …